INRA, Micalis UMR1319, France

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis

Nalini Ramarao¹, Christina Nielsen-Leroux¹, Didier Lereclus¹

Oral and intra haemocolic infection of larvae of the greater wax moth Galleria mellonella is described. This insect can be used to study virulence factors of entomopathogenic as well as mammalian opportunistic bacteria. Rearing of the insects, methods of infection and examples of in vivo analysis are described.