Humboldt Universität zu Berlin

2 ARTICLES PUBLISHED IN JoVE

Medicine

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Johanna Hamel^1,2, Antje Kraft¹, Sven Ohl³, Sophie De Beukelaer¹, Heinrich J. Audebert^1,2, Stephan A. Brandt¹

¹Department of Neurology, Universitätsmedizin Charité, ²Center for Stroke Research Berlin (CSB), Universitätsmedizin Charité, ³Berlin School of Mind and Brain, Humboldt Universität zu Berlin

Patients with visual deficits after stroke report about different constraints in daily life most likely due to variable compensatory strategies, which are difficult to differentiate in clinical routine. We present a clinical set-up which allows measurement of different compensatory head- and eye-movement-strategies and evaluating their effects on driving performance.

Neuroscience

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging

Filip Niemann^*1, Alireza Shababaie^*1, Sven Paßmann¹, Steffen Riemann¹, Robert Malinowski¹, Harund Kocataş¹, Leonardo M. Caisachana Guevara^1,2, Mohamed Abdelmotaleb¹, Daria Antonenko¹, Felix Blankenburg^3,4, Rico Fischer², Gesa Hartwigsen^5,6, Shu-Chen Li^7,8, Michael A. Nitsche^9,10,11, Axel Thielscher^12,13, Dagmar Timmann¹⁴, Anna Fromm¹, Dayana Hayek¹, Ann-Kathrin Hubert¹, Andrew K. Martin^15,16, Alexander Hunold¹⁷, Agnes Flöel^*1,18, Marcus Meinzer^*1

¹Department of Neurology, University Medicine Greifswald, ²Department of Psychology, University Medicine Greifswald, ³Berlin School of Mind and Brain, Humboldt Universität zu Berlin, ⁴Neurocomputation and Neuroimaging Unit, Freie Universität Berlin, ⁵Wilhelm-Wundt-Institute for Psychology, Cognitive and Biological Psychology, Leipzig University, ⁶Lise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, ⁷Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, ⁸Centre for Tactile Internet with Human-in-the-Loop, Technische Universität Dresden, ⁹Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, ¹⁰German Centre for Mental Health (DZPG), ¹¹Clinic of Psychiatry and Psychotherapy, Protestant Hospital of Bethel Foundation, University Hospital OWL, Bielefeld University, ¹²Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Amager and Hvidovre, ¹³Department of Health Technology, Technical University of Denmark, ¹⁴Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Essen University Hospital, ¹⁵Department of Psychology, University of Kent, ¹⁶Kent Medway Medical School, ¹⁷Institute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, ¹⁸German Center for Neurodegenerative Diseases (DZNE Site Greifswald)

This protocol describes the method of neuronavigated electrode placement for focal, transcranial direct current stimulation (tDCS) administered during functional magnetic resonance imaging (fMRI).