Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber ModelNeveda Naz 1, Dominic C. Mills 1, Brendan W. Wren 1, Nick Dorrell 1
1Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine
Performing cell culture assays for investigating bacterial adhesion and invasion under aerobic conditions is usually unrepresentative of the in vivo environment. A Vertical Diffusion Chamber model allows study of interactions of the human pathogen Campylobacter jejuni with intestinal epithelial cells under more in vivo-like conditions, resulting in enhanced bacterial invasion.
