Neuronal morphogenesis and migration are crucial events underlying proper brain development. Here, we describe methods to genetically manipulate cultured cerebellar granule neurons and the developing cerebellum for the assessment of morphology and migratory characteristics of neurons.

genetic-manipulation-cerebellar-granule-neurons-vitro-vivo-to-study

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

Developmental events in the brain including neuronal morphogenesis and migration are highly orchestrated processes. In vitro and in vivo analyses allow ...

Institution - Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB)

Articles Published in JoVE