University of Puerto Rico-Aguadilla

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

A Method to Inflict Closed Head Traumatic Brain Injury in Drosophila

Rebeccah J. Katzenberger¹, Carin A. Loewen², R. Tayler Bockstruck¹, Mikal A. Woods³, Barry Ganetzky², David A. Wassarman¹

¹Department of Cell and Regenerative Biology, University of Wisconsin-Madison, ²Department of Genetics, University of Wisconsin-Madison, ³Department of Natural Sciences, University of Puerto Rico-Aguadilla

Here we describe a method to inflict closed head traumatic brain injury (TBI) in Drosophila. This method provides a gateway to investigate the cellular and molecular mechanisms that underlie TBI pathologies using the vast array of experimental tools and techniques available for flies.