Caspase-3 Activity in the Rat Amygdala Measured by Spectrofluorometry After Myocardial InfarctionKim Gilbert 1, Roger Godbout 1, Guy Rousseau 1
1Centre de Recherche, Hospital du Sacre-Coeur de Montreal
Myocardial infarction (MI) is not only followed by impaired cardiac function but also by apoptosis in the amygdala, a brain region involved in the behavioral consequences of MI. This protocol describes how to induce MI, collect amygdala tissue and measure caspase-3 activity, a marker of apoptosis, therein.