Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish BrainJeroen Kuipers 1, Ruby D. Kalicharan 1, Anouk H. G. Wolters 1, Tjakko J. van Ham *2, Ben N.G. Giepmans *1
1Cell Biology, UMC Groningen, 2Clinical Genetics, Erasmus MC Rotterdam
Large-scale 2D electron microscopy (EM), or nanotomy, is the tissue-wide application of nanoscale resolution EM. Here we describe a universal method for nanotomy applied to investigate the zebrafish larval brain in health and upon non-invasive brain injury.
