Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female MiceAnna Zychlinsky Scharff 1, Matthew L. Albert 1,2, Molly A. Ingersoll 1
1Unité d’Immunobiologie des Cellules Dendritiques, Department of Immunology, Institut Pasteur, INSERM U818, 2Genentech
The established model of transurethral catheterization of mice allows the study of bladder pathologies, including urinary tract infection, but can only be performed in females. A new model of male transurethral instillation, presented here, will enable research in an area marked by strong clinical and epidemiological differences between the sexes.