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Japan Tobacco Inc.

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
Hironori Nishitsuji 1, Hiromi Yamamoto 1, Ritsuko Shiina 1, Keisuke Harada 2, Saneyuki Ujino 1, Kunitada Shimotohno 1
1Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 2Central Pharmaceutical Research Institute, Japan Tobacco Inc.

Here we describe a newly developed hepatitis B virus (HBV) reporter system to monitor the early stages of the HBV life cycle. This simplified in vitro system will aid in the screening of anti-HBV agents using a high-throughput strategy.

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