Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron OverloadBérengère Koehl 1, Florence Missud 1, Laurent Holvoet 1, Ghislaine Ithier 1, Oliver Sakalian-Black 2, Zinedine Haouari 1, Emmanuelle Lesprit 3, André Baruchel 4, Malika Benkerrou 1
1Reference Centre of Sickle Cell Disease, Hematology Unit, Robert Debré Hospital, AP-HP, 2School of Pharmacy, Université Paris Descartes, 3Etablissement Français du Sang, Robert Debré Hospital, AP-HP, 4Hematology Unit,, Robert Debré Hospital, AP-HP, Univsité Paris Diderot
We have outlined a method of continuous manual exchange transfusion for the treatment of sickle cell disease in patients. This safe protocol was designed to effectively limit iron overload in patients in need of chronic transfusions and can be used extensively without any special equipment.