NYITCOM-A-State

1 ARTICLES PUBLISHED IN JoVE

Developmental Biology

Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish

Rohan Datta¹, Ada Wong¹, Troy Camarata², Farhana Tamanna¹, Imran Ilahi¹, Aleksandr Vasilyev¹

¹Department of Biomedical Sciences, NYITCOM, ²Department of Basic Sciences, NYITCOM-A-State

This work presents a new in vivo model of segmental kidney injury using kidney GFP transgenic zebrafish. The model allows for the induction of the targeted ablation of kidney epithelial cells to show the cellular mechanisms of nephron injury and repair.