Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of SamplesRyan S Thwaites 1, Hannah C Jarvis 1, Nehmat Singh 1, Akhilesh Jha 1, Andy Pritchard 2, Hailing Fan 1, Tanushree Tunstall 1, Joan Nanan 1, Simon Nadel 2, Onn Min Kon 2, Peter J Openshaw 1, Trevor T Hansel 1
1National Heart and Lung Institute, Faculty of Medicine, Imperial College London, St Mary's Hospital, 2St Mary's Hospital, Imperial College Healthcare Trust
This manuscript describes the use of nasal and bronchial absorption techniques, specifically using synthetic absorptive matrices (SAM) to sample the mucosal lining fluid (MLF) of the upper and lower airway. These methods provide better standardization and tolerability than existing respiratory sampling techniques.
