Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A NeurotransmissionFrédéric Knoflach 1, Maria-Clemencia Hernandez 1, Daniel Bertrand 2
1Discovery Neuroscience, Pharma Research and Early Development, Roche Innovation Center Basel, 2HiQScreen Sàrl 6
Here, we present protocols to discover compounds active at GABAA receptors, from the binding to the physiology and pharmacology.