Tri-Service General Hospital, National Defense Medical Center

2 ARTICLES PUBLISHED IN JoVE

Medicine

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Gang-Yi Fan¹, Juin-Hong Cherng^2,3, Shu-Jen Chang⁴, Raju Poongodi², Chih-Hsin Wang⁵, Yi-Wen Wang², Yao-Horng Wang⁶, Cheng-Che Liu⁷, En Meng⁸

¹Graduate Institute of Medical Sciences, National Defense Medical Center, ²Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, ³Department of Gerontological Health Care, National Taipei University of Nursing and Health Sciences, ⁴Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, ⁵Department of Plastic and Reconstructive Surgery, Tri-Service General Hospital, ⁶Department of Nursing, Yuanpei University, ⁷Department of Physiology and Biophysics; Graduate Institute of Physiology, National Defense Medical Center, ⁸Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center

To closely mimic the mode of burn injuries requires the interplay between clinical observation and studies in animal models. In this study, a swine model of severe burn injury was established to assess an experimental dressing in physiological and pathophysiological settings.

Bioengineering

Wet-spinning-based Molding Process of Gelatin for Tissue Regeneration

Chia-Yu Wang¹, Dewi Sartika², Ding-Han Wang³, Po-Da Hong¹, Juin-Hong Cherng^2,4,5, Shu-Jen Chang^2,6, Cheng-Che Liu⁷, Yi-Wen Wang⁴, Sheng-Tang Wu⁸

¹Department of Materials Science and Engineering, National Taiwan University of Science and Technology, ²Laboratory of Adult Stem Cell and Tissue Regeneration, National Defense Medical Center, ³School of Dentistry, National Yang-Ming University, ⁴Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, ⁵Department of Gerontological Health Care, National Taipei University of Nursing and Health Sciences, ⁶Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, ⁷Department of Physiology and Biophysics, Graduate Institute of Physiology, National Defense Medical Center, ⁸Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center

We developed and describe a protocol based on the wet spinning concept, for the construction of gelatin-based biomaterials used for the application of tissue engineering.