Nondestructive Monitoring of Degradable Scaffold-Based Tissue-Engineered Blood Vessel Development Using Optical Coherence TomographyWanwen Chen 1, Shangmin Liu 2, Junqing Yang 1, Yueheng Wu 2, Wentao Ma 2, Zhanyi Lin 3
1Department of Cardiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 2Medical Research Center, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 3Institute of Geriatric medicine, Guangdong Academy of Medical Sciences, Guangdong General Hospital
A step by step protocol for nondestructive and long-period monitoring the process of vascular remodeling and scaffold degradation in real-time culture of biodegradable polymeric scaffold-based tissue-engineered blood vessels with pulsatile stimulation using optical coherence tomography is described here.