Detection of Endotoxin in Nano-formulations Using Limulus Amoebocyte Lysate (LAL) AssaysBarry W. Neun 1, Marina A. Dobrovolskaia 1
1Nanotechnology Characterization Lab., Cancer Research Technology Program, Frederick National Laboratory for Cancer Research sponsored by National Cancer Institute
Detection of endotoxins in engineered nanomaterials represents one of the grand challenges in the field of nanomedicine. Here, we present a case study that describes the framework composed of three different LAL formats to estimate potential endotoxin contamination in nanoparticles.