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Biomedical Sciences Research Centre "Al. Fleming"

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains
Myrto Denaxa 1,2, Guilherme Neves 3, Juan Burrone 3, Vassilis Pachnis 1
1Nervous System Development and Homeostasis Laboratory, The Francis Crick Institute, 2Neuroscience Centre, Biomedical Sciences Research Centre "Al. Fleming", 3Centre for Developmental Neurobiology, King's College London

Here we present a protocol, designed to use chemogenetic tools to manipulate the activity of cortical interneuron progenitors transplanted into the cortex of early postnatal mice.

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