Renal Subcapsular Transplantation of 2'-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude MiceJianxue Wang 1,3,4, Guolin Chen 1,3,4, Qianwen Cui 2,3,4, Erfei Song 1,3,4, Weihua Tao 1, Wanqun Chen 2, Cunchuan Wang 1,3,4, Shiqi Jia 1,3,4
1The First Affiliated Hospital, Jinan University, 2Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Jinan University, 3The Institute of Clinical Medicine, Jinan University, 4Joint institute of Metabolic Medicine Between Jinan University and University of Hong Kong
We provide a simple and efficient method to transplant 2’-deoxyguanosine treated E18.5 thymus into the renal capsule of a nude mouse. This method should aide in the study of both thymic epithelial cells function and T cells maturation.