Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric ApproachLesheng Zhang *1, Tom Cambron *2, Yueqing Niu 1, Zigang Xu 3, Ning Su 4, Hongyan Zheng 4, Karl Wei 2, Paula Ray 2
1Procter and Gamble, Beijing Innovative center, 2Procter and Gamble, Mason Business Center, 3Department of Dermatology, Beijing Children's Hospital, 4Chinese Academy of Inspection and Quarantine
Here, we present a protocol for collection of confocal Raman spectra from human subjects in clinical studies combined with chemometric approaches for spectral outlier removal and the subsequent extraction of key features.
