Université de Toulouse, CNRS

1 ARTICLES PUBLISHED IN JoVE

Chemistry

Versatile CO₂ Transformations into Complex Products: A One-pot Two-step Strategy

Sarah Desmons^*1,2, Dan Zhang^*1, Angelica Mejia Fajardo¹, Sebastien Bontemps¹

¹LCC-CNRS, Université de Toulouse, CNRS, ²LISBP, Université de Toulouse, CNRS, INRA, INSA

CO₂ transformations are conducted in a one-pot two-step procedure for the synthesis of complex molecules. The selective 4 e^- reduction of CO₂ with a hydroborane reductant affords a reactive and versatile bis(boryl)acetal intermediate which is subsequently involved in condensation reaction or carbene-mediated C-C coupling generation.