Universidad Cardenal Herrera-CEU

2 ARTICLES PUBLISHED IN JoVE

Neuroscience

GM-Free Generation of Blood-Derived Neuronal Cells

Zorica A. Becker-Kojić¹, Anne-Kathrin Schott¹, Ivan Zipančić², Vicente Hernández-Rabaza²

¹ACA CELL Biotech GmbH, ²Departmento Ciencias Biomedicas, Universidad Cardenal Herrera-CEU

We present a genetically modified-free (GM-free) method to obtain cells with a neuronal phenotype from reprogrammed peripheral blood cells. Activation of a signaling pathway linked to novel human GPI-linked protein reveals an efficient GM-free method for obtaining human pluripotent stem cells.

Bioengineering

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies

Anne-Kathrin Schott¹, Ivan Zipančić², Vicente Hernández-Rabaza², Zorica A. Becker-Kojić¹

¹ACA CELL Biotech GmbH, ²Departamento Ciencias Biomédicas, Universidad Cardenal Herrera-CEU

Here we present a non-genetic method to generate human autologous liver spheroids using mononuclear cells isolated from steady-state peripheral blood.