Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration StrategyBenjamín León-Mancilla 1,2, Moisés Martínez-Castillo 1, Zaira Medina-Avila 1, Armando Pérez-Torres 3, Jorge Garcia-Loya 2, Ana Alfaro-Cruz 4, Cristina Piña-Barba 5, Gabriela Gutierrez-Reyes 1
1Liver, Pancreas and Motility Laboratory; Unit of Experimental Medicine; School of Medicine, Universidad Nacional Autónoma de Mexico (UNAM), 2Department of Surgery, School of Medicine, Universidad Nacional Autónoma de México (UNAM), 3Department of Cells and Tissue Biology, School of Medicine, Universidad Nacional Autónoma de México (UNAM), 4Department of Pathology, Hospital General de Mexico, 5Materials Research Institute, Universidad Nacional Autónoma de México (UNAM)
Liver diseases are induced by many causes that promote fibrosis or cirrhosis. Transplantation is the only option for recovering health. However, given the scarcity of transplantable organs, alternatives must be explored. Our research proposes the implantation of collagen scaffolds in liver tissue from an animal model.
