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Jawaharlal Nehru University New Delhi

1 ARTICLES PUBLISHED IN JoVE

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Biochemistry

CD Spectroscopy to Study DNA-Protein Interactions
Vijendra Arya 1, Anindita Dutta 1, Rohini Muthuswami 1
1Jawaharlal Nehru University New Delhi

The interaction of an ATP-dependent chromatin remodeler with a DNA ligand is described using CD spectroscopy. The induced conformational changes on a gene promoter analyzed by the peaks generated can be used to understand the mechanism of transcriptional regulation.

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