<p class="jove_content">This work analyzes the vector dose and exposure time required to induce neuroinflammation, neurodegeneration, and motor impairment in this preclinical model of Parkinson&#39;s disease. These vectors encoding the human &#945;-synuclein are delivered into the substantia nigra&#160;to recapitulate the synuclein pathology associated with Parkinson&#39;s disease.</p>

analyzing-parkinson-s-disease-mouse-model-induced-adeno-associated

Institution - Buck Institute for Research on Ageing

Articles Published in JoVE