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The Seventh Affiliated Hospital of Sun Yat-sen University

3 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Osmotic Pump-based Drug-delivery for In Vivo Remyelination Research on the Central Nervous System
Xiaorui Wang 1, Yixun Su 1,2, Xuelian Hu 1,3, Jianqin Niu 1
1Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain, and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, 2Research Centre, The Seventh Affiliated Hospital of Sun Yat-sen University, 3School of Medicine, Chongqing University

Demyelination takes place in multiple central nervous system diseases. A reliable in vivo drug delivery technique is necessary for remyelinating drug testing. This protocol describes an osmotic pump-based method that allows long-term drug delivery directly into the brain parenchyma and improves the drug bioavailability, with broad application in remyelination research.

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Neuroscience

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke
Yongchun Jiang *1,2,3, Junxiao Yin *4, Biyi Zhao 1,3,5, Yajie Zhang 1,3, Tingting Peng 1,3, Wanqi Zhuang 1,3, Siqing Wang 1,3, Siqi Huang 1,3, Meilian Zhong 1,3, Yanni Zhang 1,3, Guibing Tang 1,3, Bingchi Shen 6, Haining Ou 1,3, Yuxin Zheng *2,3, Qiang Lin *2,3
1Guangzhou Medical University, 2Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University, 3Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University, 4Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, 5School of Traditional Chinese Medicine, Jinan University, 6Department of Stomatology, Second Clinical Medical College, Dongguan Campus of Guangdong Medical University

The purpose of this study is to provide an important reference for the standard clinical operation of motor imagery brain-computer interface (MI-BCI) for upper limb motor dysfunction after stroke.

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Neuroscience

Scalp Acupuncture Synchronizing Dual Task Gait for Enhancing Prefrontal Cortex Response
Jun Su 1, Yuanyuan Guo 2, Biyi Zhao 3, Yongchun Jiang 2,4,5, Xi Qin 6, Meilian Zhong 2,4,5, Dathan Nevin Dychingco Leung 7, Junxiao Yin 8, Qiang Lin *4, Ke Chen *9
1Department of Orthopaedics, Anshun Hospital of Traditional Chinese Medicine, 2The Fifth Affiliated Hospital of Guangzhou Medical University, 3School of Traditional Chinese Medicine, Jinan University, 4Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University, 5Guangzhou Medical University, 6Panzhihua Central Hospital, 7Department of Physical Therapy, College of Rehabilitation Sciences, University of Santo Tomas, 8Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, 9Department of Spine Surgery, Zhongshan Torch Development Zone People's Hospital

This protocol demonstrates the standardized procedure of scalp acupuncture synchronizing motor-cognitive dual task and motor-cognitive dual task. This can provide an important reference for the clinical exploration of the new and effective non-drug treatment of integrated Chinese and Western medicine.

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