The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in HumansBethany L. Stangl 1, Nia D. Byrd 1, Soundarya Soundararajan 1, Martin H. Plawecki 2, Sean O’Connor 2,3, Vijay A. Ramchandani 1
1Human Psychopharmacology Laboratory, Division of Intramural Clinical and Biological Research, NIAAA, 2Dept. of Psychiatry, Indiana University School of Medicine, 3R.L. Roudebush VA Medical Center
This study aims to show that the Progressive-Ratio Computer-assisted Alcohol-Infusion System (CAIS) paradigm is a reliable and sensitive method that can be used to examine the motivating properties associated with alcohol self-administration in humans.
