Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain AssayBasak Donertas-Ayaz 1, Ariana C. Brice-Tutt 2, Wendi L. Malphurs 2, Darrice Montgomery 2, Richard H. Mills 3, John K. Neubert 2, Robert M. Caudle 1
1Department of Oral and Maxillofacial Surgery, University of Florida, Gainesville, 2Department of Orthodontics, University of Florida, Gainesville, 3Stoelting Co. Wood Dale
This protocol describes the assessment of mechanical hypersensitivity in a rat model of neuropathic orofacial pain using an operant-based orofacial pain assessment device.