Development of a Uterosacral Ligament Suspension Rat ModelBeverly J. Miller 1, Brian K. Jones 2, Jonathan S. Turner 3, Steven R. Caliari 1,3, Monique H. Vaughan 4
1Department of Chemical Engineering, University of Virginia, 2Electrophysiology Division, Abbott, 3Department of Biomedical Engineering, University of Virginia, 4Department of Obstetrics and Gynecology, Division of Pelvic Medicine and Reconstructive Surgery, University of Virginia
Pelvic organ prolapse affects millions of women worldwide and yet some common surgical interventions have failure rates as high as 40%. The lack of standard animal models to investigate this condition impedes progress. We propose the following protocol as a model for uterosacral ligament suspension and in vivo tensile testing.
