University of Macau, Avenida da Universidade

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

Brain Ventricular Microinjections of Lipopolysaccharide into Larval Zebrafish to Assess Neuroinflammation and Neurotoxicity

Yulin He¹, Simon Ming Yuen Lee^1,2

¹State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, ²Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Avenida da Universidade

This protocol demonstrates the microinjection of lipopolysaccharide into the brain ventricular region in a zebrafish larval model to study the resulting neuroinflammatory response and neurotoxicity.