A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow ReactorZhangtao Zhou 1,2, Yang Wang 1, Shuqiang Liu 1, Andrew Phillis 1,2, Qijun Zhang 1, Weiping Ye 1
1Shenzhen Hwagen Pharmaceutical Co., Ltd, 2Guangdong Raffles Pharmaceutical Technology Co., Ltd
A detailed scalable continuous flow protocol is presented to synthesize an aryl fluoride from an aryl amine through the Balz-Schiemann reaction.