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Guangdong Raffles Pharmaceutical Technology Co., Ltd

1 ARTICLES PUBLISHED IN JoVE

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Chemistry

A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor
Zhangtao Zhou 1,2, Yang Wang 1, Shuqiang Liu 1, Andrew Phillis 1,2, Qijun Zhang 1, Weiping Ye 1
1Shenzhen Hwagen Pharmaceutical Co., Ltd, 2Guangdong Raffles Pharmaceutical Technology Co., Ltd

A detailed scalable continuous flow protocol is presented to synthesize an aryl fluoride from an aryl amine through the Balz-Schiemann reaction.

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