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University of Southern Mississippi

1 ARTICLES PUBLISHED IN JoVE

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Biochemistry

A Polyaniline-based Sensor of Nucleic Acids
Partha Pratim Sengupta 1, Jared N. Gloria 1, Marcus K. Parker 1, Alex S. Flynt 1
1Department of Biological Sciences, University of Southern Mississippi

Nucleic acids are common analytes for assessing biological systems; however, bias from enzymatic manipulation can cause concern. Here a method is described for label-free detection of nucleic acids using polyaniline. This sensitive, cost-effective sensor technology can distinguish single nucleotide differences between molecules.

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