Emory Vaccine Center at Yerkes National Primate Research Center,
Department of Pathology and Laboratory Medicine
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Molecular epidemiology of human immunodeficiency virus type 1 transmission in a heterosexual cohort of discordant couples in Zambia.
Journal of virology Jan, 2002 | Pubmed ID: 11739704
Mutation of the dominant endocytosis motif in human immunodeficiency virus type 1 gp41 can complement matrix mutations without increasing Env incorporation.
Journal of virology Apr, 2002 | Pubmed ID: 11884559
Identification of a minimal HIV-1 gag domain sufficient for self-association.
Virology Mar, 2002 | Pubmed ID: 11886273
Molecular organization of Mason-Pfizer monkey virus capsids assembled from Gag polyprotein in Escherichia coli.
Journal of virology May, 2002 | Pubmed ID: 11932398
Novel monoclonal antibody directed at the receptor binding site on the avian sarcoma and leukosis virus Env complex.
Journal of virology Aug, 2002 | Pubmed ID: 12097564
Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding.
EMBO reports Jul, 2002 | Pubmed ID: 12101095
The Mason-Pfizer monkey virus internal scaffold domain enables in vitro assembly of human immunodeficiency virus type 1 Gag.
Journal of virology Nov, 2002 | Pubmed ID: 12368324
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2002 | Pubmed ID: 12444251
A tyrosine motif in the cytoplasmic domain of mason-pfizer monkey virus is essential for the incorporation of glycoprotein into virions.
Journal of virology May, 2003 | Pubmed ID: 12692221
Progressive truncations C terminal to the membrane-spanning domain of simian immunodeficiency virus Env reduce fusogenicity and increase concentration dependence of Env for fusion.
Journal of virology Jun, 2003 | Pubmed ID: 12768026
Variable sensitivity to substitutions in the N-terminal heptad repeat of Mason-Pfizer monkey virus transmembrane protein.
Journal of virology Jul, 2003 | Pubmed ID: 12829817
Membrane transplantation to correct integral membrane protein defects.
Journal of molecular medicine (Berlin, Germany) Aug, 2003 | Pubmed ID: 12879148
The M-PMV cytoplasmic targeting-retention signal directs nascent Gag polypeptides to a pericentriolar region of the cell.
Traffic (Copenhagen, Denmark) Oct, 2003 | Pubmed ID: 12956869
M-PMV capsid transport is mediated by Env/Gag interactions at the pericentriolar recycling endosome.
Traffic (Copenhagen, Denmark) Oct, 2003 | Pubmed ID: 12956870
Positive and negative modulation of virus infectivity and envelope glycoprotein incorporation into virions by amino acid substitutions at the N terminus of the simian immunodeficiency virus matrix protein.
Journal of virology Oct, 2003 | Pubmed ID: 14512538
The endogenous langur type D retrovirus PO-1-Lu and its exogenous counterparts in macaque and langur monkeys.
Virology Oct, 2003 | Pubmed ID: 14585330
Source and filter adjustments affecting the perception of the vocal qualities twang and yawn.
Logopedics, phoniatrics, vocology , 2003 | Pubmed ID: 14686543
Public health. A sound rationale needed for phase III HIV-1 vaccine trials.
Science (New York, N.Y.) Jan, 2004 | Pubmed ID: 14726576
Comparison of human, canine, and ovine laryngeal dimensions.
The Annals of otology, rhinology, and laryngology Jan, 2004 | Pubmed ID: 14763576
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission.
Science (New York, N.Y.) Mar, 2004 | Pubmed ID: 15044802
A three-dimensional model of vocal fold abduction/adduction.
The Journal of the Acoustical Society of America Apr, 2004 | Pubmed ID: 15101653
An early stage of Mason-Pfizer monkey virus budding is regulated by the hydrophobicity of the Gag matrix domain core.
Journal of virology May, 2004 | Pubmed ID: 15113883
Normal vibration frequencies of the vocal ligament.
The Journal of the Acoustical Society of America May, 2004 | Pubmed ID: 15139637
Determinants of human immunodeficiency virus type 1 baseline susceptibility to the fusion inhibitors enfuvirtide and T-649 reside outside the peptide interaction site.
Journal of virology Jul, 2004 | Pubmed ID: 15220433
Second-site revertants of a simian immunodeficiency virus gp41 mutant defective in envelope glycoprotein incorporation.
AIDS research and human retroviruses Jul, 2004 | Pubmed ID: 15307919
Antigenic conservation and immunogenicity of the HIV coreceptor binding site.
The Journal of experimental medicine May, 2005 | Pubmed ID: 15867093
Active and passive properties of canine abduction/adduction laryngeal muscles.
Journal of voice : official journal of the Voice Foundation Sep, 2005 | Pubmed ID: 16102663
Amino acid residues in the cytoplasmic domain of the Mason-Pfizer monkey virus glycoprotein critical for its incorporation into virions.
Journal of virology Sep, 2005 | Pubmed ID: 16140733
Activity of the Mason-Pfizer monkey virus fusion protein is modulated by single amino acids in the cytoplasmic tail.
Journal of virology Sep, 2005 | Pubmed ID: 16140734
Point mutations in the C-terminus of HIV-1 gp160 reduce apoptosis and calmodulin binding without affecting viral replication.
Virology Jan, 2006 | Pubmed ID: 16229872
The RNA binding G-patch domain in retroviral protease is important for infectivity and D-type morphogenesis of Mason-Pfizer monkey virus.
The Journal of biological chemistry Dec, 2005 | Pubmed ID: 16257973
Individual subject laryngeal dimensions of multiple mammalian species for biomechanical models.
The Annals of otology, rhinology, and laryngology Oct, 2005 | Pubmed ID: 16285273
Comparison of the produced and perceived voice range profiles in untrained and trained classical singers.
Journal of voice : official journal of the Voice Foundation Dec, 2006 | Pubmed ID: 16325373
Review of range of arytenoid cartilage motion.
Acoustics research letters online : ARLO , 2000 | Pubmed ID: 16570110
Juxtamembrane protein segments that contribute to recruitment of cholesterol into domains.
Biochemistry May, 2006 | Pubmed ID: 16681383
Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1.
Journal of virology Jun, 2006 | Pubmed ID: 16699001
Real-time PCR quantitation of subtype C HIV DNA in a Zambian discordant couple cohort.
AIDS research and human retroviruses May, 2006 | Pubmed ID: 16706621
Distinct roles for nucleic acid in in vitro assembly of purified Mason-Pfizer monkey virus CANC proteins.
Journal of virology Jul, 2006 | Pubmed ID: 16809314
Sensitivity of elastic properties to measurement uncertainties in laryngeal muscles with implications for voice fundamental frequency prediction.
Journal of voice : official journal of the Voice Foundation Nov, 2007 | Pubmed ID: 16904867
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.
Journal of virology Dec, 2006 | Pubmed ID: 16971434
Objective measurement of vocal fatigue in classical singers: a vocal dosimetry pilot study.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Oct, 2006 | Pubmed ID: 17011424
Novel approach for differential diagnosis of HIV infections in the face of vaccine-generated antibodies: utility for detection of diverse HIV-1 subtypes.
Journal of acquired immune deficiency syndromes (1999) Nov, 2006 | Pubmed ID: 17019363
The betaretrovirus Mason-Pfizer monkey virus selectively excludes simian APOBEC3G from virion particles.
Journal of virology Dec, 2006 | Pubmed ID: 17035335
A plea for justice for jailed medical workers.
Science (New York, N.Y.) Nov, 2006 | Pubmed ID: 17062652
Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2006 | Pubmed ID: 17142324
Voicing and silence periods in daily and weekly vocalizations of teachers.
The Journal of the Acoustical Society of America Jan, 2007 | Pubmed ID: 17297801
Investigating the utility of the HIV-1 BED capture enzyme immunoassay using cross-sectional and longitudinal seroconverter specimens from Africa.
AIDS (London, England) Feb, 2007 | Pubmed ID: 17301558
Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.
Journal of virology Jun, 2007 | Pubmed ID: 17360739
Refinements in modeling the passive properties of laryngeal soft tissue.
Journal of applied physiology (Bethesda, Md. : 1985) Jul, 2007 | Pubmed ID: 17412782
A two-dimensional biomechanical model of vocal fold posturing.
The Journal of the Acoustical Society of America Apr, 2007 | Pubmed ID: 17471739
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
Journal of virology Aug, 2007 | Pubmed ID: 17507468
Basic residues in the Mason-Pfizer monkey virus gag matrix domain regulate intracellular trafficking and capsid-membrane interactions.
Journal of virology Sep, 2007 | Pubmed ID: 17596311
HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice.
Vaccine Sep, 2007 | Pubmed ID: 17706843
Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.
Journal of virology Nov, 2007 | Pubmed ID: 17728232
Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV.
Biochemistry Jan, 2008 | Pubmed ID: 18081318
Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing.
Journal of virology Apr, 2008 | Pubmed ID: 18256145
Breath acidification in adolescent runners exposed to atmospheric pollution: a prospective, repeated measures observational study.
Environmental health : a global access science source , 2008 | Pubmed ID: 18328105
Role of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein in cell-cell fusion and virus infection.
Journal of virology Jun, 2008 | Pubmed ID: 18353944
Importance of the membrane-perturbing properties of the membrane-proximal external region of human immunodeficiency virus type 1 gp41 to viral fusion.
Journal of virology Jun, 2008 | Pubmed ID: 18353966
Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients.
The Journal of experimental medicine May, 2008 | Pubmed ID: 18426987
D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2008 | Pubmed ID: 18647839
Human leukocyte antigen class I genotypes in relation to heterosexual HIV type 1 transmission within discordant couples.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2008 | Pubmed ID: 18684953
The effect of point mutations within the N-terminal domain of Mason-Pfizer monkey virus capsid protein on virus core assembly and infectivity.
Virology Oct, 2008 | Pubmed ID: 18755489
Identification of postentry restrictions to Mason-Pfizer monkey virus infection in New World monkey cells.
Journal of virology Nov, 2008 | Pubmed ID: 18799582
Large changes in the CRAC segment of gp41 of HIV do not destroy fusion activity if the segment interacts with cholesterol.
Biochemistry Nov, 2008 | Pubmed ID: 18937430
The impact of altered polyprotein ratios on the assembly and infectivity of Mason-Pfizer monkey virus.
Virology Feb, 2009 | Pubmed ID: 19062065
Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1.
PLoS pathogens Jan, 2009 | Pubmed ID: 19165325
A comparison of a child's fundamental frequencies in structured elicited vocalizations versus unstructured natural vocalizations: a case study.
International journal of pediatric otorhinolaryngology Apr, 2009 | Pubmed ID: 19185926
Adaptation of HIV-1 to human leukocyte antigen class I.
Nature Apr, 2009 | Pubmed ID: 19242411
Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients.
The Journal of experimental medicine Apr, 2009 | Pubmed ID: 19307327
Viral characteristics of transmitted HIV.
Current opinion in HIV and AIDS Jan, 2008 | Pubmed ID: 19372939
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.
The Journal of experimental medicine Jun, 2009 | Pubmed ID: 19487424
Heterosexual transmission of human immunodeficiency virus type 1 subtype C: Macrophage tropism, alternative coreceptor use, and the molecular anatomy of CCR5 utilization.
Journal of virology Aug, 2009 | Pubmed ID: 19515785
The inability to produce soft voice (IPSV): a tool to detect vocal change in school-teachers.
Logopedics, phoniatrics, vocology , 2009 | Pubmed ID: 19565404
Cervids with different vocal behavior demonstrate different viscoelastic properties of their vocal folds.
Journal of morphology Jan, 2010 | Pubmed ID: 19603411
Quantifying vocal fatigue recovery: dynamic vocal recovery trajectories after a vocal loading exercise.
The Annals of otology, rhinology, and laryngology Jun, 2009 | Pubmed ID: 19663377
Truncation of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein defines elements required for fusion, incorporation, and infectivity.
Journal of virology Nov, 2009 | Pubmed ID: 19726514
Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways.
PLoS pathogens Sep, 2009 | Pubmed ID: 19763269
OVERLAP OF HEARING AND VOICING RANGES IN SINGING.
Journal of singing : the official journal of the National Association of Teachers of Singing Apr, 2005 | Pubmed ID: 19844607
HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.
Journal of clinical microbiology Jan, 2010 | Pubmed ID: 19906903
CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription.
The Journal of experimental medicine Jan, 2010 | Pubmed ID: 20065064
Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry.
Journal of virology Apr, 2010 | Pubmed ID: 20147398
Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships.
PloS one , 2010 | Pubmed ID: 20224785
XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH.
Urology Apr, 2010 | Pubmed ID: 20371060
Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells.
Journal of virology Jul, 2010 | Pubmed ID: 20410264
Measuring HIV fusion mediated by envelopes from primary viral isolates.
Methods (San Diego, Calif.) Jan, 2011 | Pubmed ID: 20554044
Residues in the membrane-spanning domain core modulate conformation and fusogenicity of the HIV-1 envelope glycoprotein.
Virology Sep, 2010 | Pubmed ID: 20605619
Variations in intensity, fundamental frequency, and voicing for teachers in occupational versus nonoccupational settings.
Journal of speech, language, and hearing research : JSLHR Aug, 2010 | Pubmed ID: 20689046
Vocal power and pressure-flow relationships in excised tiger larynges.
The Journal of experimental biology Nov, 2010 | Pubmed ID: 21037066
Transmitted HIV type 1 drug resistance among individuals with recent HIV infection in East and Southern Africa.
AIDS research and human retroviruses Jan, 2011 | Pubmed ID: 21091377
The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms.
Journal of virology Feb, 2011 | Pubmed ID: 21106744
Impact of a functional KIR2DS4 allele on heterosexual HIV-1 transmission among discordant Zambian couples.
The Journal of infectious diseases Feb, 2011 | Pubmed ID: 21216870
Feasibility of measurement of a voice range profile with a semi-occluded vocal tract.
Logopedics, phoniatrics, vocology Apr, 2011 | Pubmed ID: 21244326
Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals.
The Journal of infectious diseases Jan, 2011 | Pubmed ID: 21288826
Suitability of dysphonia measurements for telemonitoring of Parkinson's disease.
IEEE transactions on bio-medical engineering Apr, 2009 | Pubmed ID: 21399744
Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.
Retrovirology , 2011 | Pubmed ID: 21429204
Indeterminate and discrepant rapid HIV test results in couples' HIV testing and counselling centres in Africa.
Journal of the International AIDS Society , 2011 | Pubmed ID: 21477317
Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model.
PloS one , 2011 | Pubmed ID: 21494670
Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity.
Retrovirology , 2011 | Pubmed ID: 21569545
Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes.
Journal of virology Sep, 2011 | Pubmed ID: 21715491
Gender differences affecting vocal health of women in vocally demanding careers.
Logopedics, phoniatrics, vocology Oct, 2011 | Pubmed ID: 21722077
Disparate associations of HLA class I markers with HIV-1 acquisition and control of viremia in an African population.
PloS one , 2011 | Pubmed ID: 21858133
Role of donor genital tract HIV-1 diversity in the transmission bottleneck.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22065783
Prevalence of seroconversion symptoms and relationship to set-point viral load: findings from a subtype C epidemic, 1995-2009.
AIDS (London, England) Jan, 2012 | Pubmed ID: 22089380
Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity.
Journal of virology Mar, 2012 | Pubmed ID: 22238317
Impact of four nonclinical speaking environments on a child's fundamental frequency and voice level: a preliminary case study.
Language, speech, and hearing services in schools Jul, 2012 | Pubmed ID: 22269586
Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses.
Retrovirology , 2012 | Pubmed ID: 22433432
Teacher response to ambulatory monitoring of voice.
Logopedics, phoniatrics, vocology Oct, 2012 | Pubmed ID: 22443101
HLA-B signal peptide polymorphism influences the rate of HIV-1 acquisition but not viral load.
The Journal of infectious diseases Jun, 2012 | Pubmed ID: 22492862
A gp41-based heteroduplex mobility assay provides rapid and accurate assessment of intrasubtype epidemiological linkage in HIV type 1 heterosexual transmission Pairs.
AIDS research and human retroviruses Dec, 2012 | Pubmed ID: 22587371
Age and speech production: a 50-year longitudinal study.
Journal of the American Geriatrics Society Jun, 2012 | Pubmed ID: 22690991
Failure of a novel, rapid antigen and antibody combination test to detect antigen-positive HIV infection in African adults with early HIV infection.
PloS one , 2012 | Pubmed ID: 22715363
Horizontal directivity of low- and high-frequency energy in speech and singing.
The Journal of the Acoustical Society of America Jul, 2012 | Pubmed ID: 22779490
The structure of myristoylated Mason-Pfizer monkey virus matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in its membrane binding.
Journal of molecular biology Oct, 2012 | Pubmed ID: 22863803
Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope.
Journal of virology Dec, 2012 | Pubmed ID: 22973023
Deletion of specific immune-modulatory genes from modified vaccinia virus Ankara-based HIV vaccines engenders improved immunogenicity in rhesus macaques.
Journal of virology Dec, 2012 | Pubmed ID: 22973033
HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection.
Retrovirology , 2012 | Pubmed ID: 22995123
HIV transmission.
Cold Spring Harbor perspectives in medicine Nov, 2012 | Pubmed ID: 23043157
Cumulative Impact of Host and Viral Factors on HIV-1 Viral Load Control during Early Infection.
Journal of virology Oct, 2012 | Pubmed ID: 23115285
Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones.
Virology Nov, 2012 | Pubmed ID: 23123038
Role of Transmitted Gag CTL Polymorphisms in Defining Replicative Capacity and Early HIV-1 Pathogenesis.
PLoS pathogens Nov, 2012 | Pubmed ID: 23209412
HLA-B*57 versus HLA-B*81 in HIV-1 Infection: Slow and Steady Wins the Race?
Journal of virology Jan, 2013 | Pubmed ID: 23365442
Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
PLoS pathogens Feb, 2013 | Pubmed ID: 23468623
Elevated rate of fixation of endogenous retroviral elements in Haplorhini TRIM5 and TRIM22 genomic sequences: impact on transcriptional regulation.
PloS one , 2013 | Pubmed ID: 23516500
Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains.
Journal of virology Feb, 2014 | Pubmed ID: 24335304
A Mason-Pfizer Monkey virus Gag-GFP fusion vector allows visualization of capsid transport in live cells and demonstrates a role for microtubules.
PloS one , 2013 | Pubmed ID: 24386297
Performance of a redesigned HIV Selectest enzyme-linked immunosorbent assay optimized to minimize vaccine-induced seropositivity in HIV vaccine trial participants.
Clinical and vaccine immunology : CVI Mar, 2014 | Pubmed ID: 24403525
Direct evidence for intracellular anterograde co-transport of M-PMV Gag and Env on microtubules.
Virology Jan, 2014 | Pubmed ID: 24418544
Dynamics of viremia in primary HIV-1 infection in Africans: insights from analyses of host and viral correlates.
Virology Jan, 2014 | Pubmed ID: 24418560
Strain modulations as a mechanism to reduce stress relaxation in laryngeal tissues.
PloS one , 2014 | Pubmed ID: 24614616
ROCK1 and LIM Kinase Modulate Retrovirus Particle Release and Cell-Cell Transmission Events.
Journal of virology Jun, 2014 | Pubmed ID: 24696479
Immunology. Immune activation with HIV vaccines.
Science (New York, N.Y.) Apr, 2014 | Pubmed ID: 24700849
Intraoral pressures produced by thirteen semi-occluded vocal tract gestures.
Logopedics, phoniatrics, vocology May, 2014 | Pubmed ID: 24865621
Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions.
Human genetics Sep, 2014 | Pubmed ID: 24969460
The perceptual significance of high-frequency energy in the human voice.
Frontiers in psychology , 2014 | Pubmed ID: 24982643
Low antibody-dependent cellular cytotoxicity responses in Zambians prior to HIV-1 intrasubtype C superinfection.
Virology Aug, 2014 | Pubmed ID: 25004405
HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck.
Science (New York, N.Y.) Jul, 2014 | Pubmed ID: 25013080