Faculty of Pharmacy
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Multi-nuclear platinum complexes encapsulated in cucurbit[n]uril as an approach to reduce toxicity in cancer treatment.
Chemical communications (Cambridge, England) Jun, 2004 | Pubmed ID: 15179496
Potential adenine and minor groove binding platinum complexes.
Journal of inorganic biochemistry Oct, 2004 | Pubmed ID: 15458819
Multi-nuclear platinum drugs: a new paradigm in chemotherapy.
Current medicinal chemistry. Anti-cancer agents May, 2005 | Pubmed ID: 15992354
Cucurbit[n]uril binding of platinum anticancer complexes.
Dalton transactions (Cambridge, England : 2003) Jan, 2006 | Pubmed ID: 16395444
Polyamide platinum anticancer complexes designed to target specific DNA sequences.
Inorganic chemistry Jul, 2006 | Pubmed ID: 16842007
Synthesis of DNA-sequence-selective hairpin polyamide platinum complexes.
Chemistry (Weinheim an der Bergstrasse, Germany) , 2007 | Pubmed ID: 17226877
The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators.
Journal of inorganic biochemistry Jul, 2007 | Pubmed ID: 17544512
DNA intercalators in cancer therapy: organic and inorganic drugs and their spectroscopic tools of analysis.
Mini reviews in medicinal chemistry Jun, 2007 | Pubmed ID: 17584161
Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Sep, 2007 | Pubmed ID: 17653578
Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles.
Dalton transactions (Cambridge, England : 2003) Nov, 2007 | Pubmed ID: 17992290
Examination of cucurbit[7]uril and its host-guest complexes by diffusion nuclear magnetic resonance.
The journal of physical chemistry. B Feb, 2008 | Pubmed ID: 18247599
Degradation of bidentate-coordinated platinum(II)-based DNA intercalators by reduced L-glutathione.
Journal of medicinal chemistry May, 2008 | Pubmed ID: 18412325
Substituted beta-cyclodextrin and calix[4]arene as encapsulatory vehicles for platinum(II)-based DNA intercalators.
Inorganic chemistry Aug, 2008 | Pubmed ID: 18597414
Improving platinum(II)-based anticancer drug delivery using cucurbit[n]urils.
Journal of inorganic biochemistry Dec, 2008 | Pubmed ID: 18653238
Anionic PAMAM dendrimers as drug delivery vehicles for transition metal-based anticancer drugs.
Journal of inorganic biochemistry Mar, 2009 | Pubmed ID: 19121543
Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2mu-dpzm]2+ and its implications for anticancer drug delivery.
Journal of inorganic biochemistry Mar, 2009 | Pubmed ID: 19171382
Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators.
Chemical communications (Cambridge, England) Mar, 2009 | Pubmed ID: 19240876
Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.
Journal of medicinal chemistry Sep, 2009 | Pubmed ID: 19658404
A chemical preformulation study of a host-guest complex of cucurbit[7]uril and a multinuclear platinum agent for enhanced anticancer drug delivery.
Dalton transactions (Cambridge, England : 2003) Oct, 2009 | Pubmed ID: 19759943
Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril.
Organic & biomolecular chemistry Feb, 2010 | Pubmed ID: 20135032
Gold nanoparticles for the improved anticancer drug delivery of the active component of oxaliplatin.
Journal of the American Chemical Society Apr, 2010 | Pubmed ID: 20225865
The status of platinum anticancer drugs in the clinic and in clinical trials.
Dalton transactions (Cambridge, England : 2003) Sep, 2010 | Pubmed ID: 20593091
Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery.
Molecular pharmaceutics Dec, 2010 | Pubmed ID: 20669974
Microwave synthesis of cucurbit[n]urils.
Future medicinal chemistry Feb, 2010 | Pubmed ID: 21426190
Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin.
Journal of inorganic biochemistry Sep, 2011 | Pubmed ID: 21704583
Cisplatin-tethered gold nanoparticles that exhibit enhanced reproducibility, drug loading, and stability: a step closer to pharmaceutical approval?
Inorganic chemistry Mar, 2012 | Pubmed ID: 22390791
Cucurbit[7]uril encapsulated cisplatin overcomes cisplatin resistance via a pharmacokinetic effect.
Metallomics : integrated biometal science Jun, 2012 | Pubmed ID: 22610518
Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity.
Dalton transactions (Cambridge, England : 2003) Oct, 2012 | Pubmed ID: 22886151
Nanoparticles: the future for platinum drugs or a research red herring?
Nanomedicine (London, England) Sep, 2012 | Pubmed ID: 22994954
DNA-based aptamer fails as a simultaneous cancer targeting agent and drug delivery vehicle for a phenanthroline-based platinum(II) complex.
Journal of inorganic biochemistry Nov, 2013 | Pubmed ID: 23954482
Topical cream-based dosage forms of the macrocyclic drug delivery vehicle cucurbit[6]uril.
PloS one , 2014 | Pubmed ID: 24454850
A cisplatin slow-release hydrogel drug delivery system based on a formulation of the macrocycle cucurbit[7]uril, gelatin and polyvinyl alcohol.
Journal of inorganic biochemistry May, 2014 | Pubmed ID: 24595010