Nancy E. Freitag

Intracellular induction of Listeria monocytogenes actA expression.

Negative regulation of PrfA, the key activator of Listeria monocytogenes virulence gene expression, is dispensable for bacterial pathogenesis.

Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products.

Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster.

Evidence implicating the 5' untranslated region of Listeria monocytogenes actA in the regulation of bacterial actin-based motility.

Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity.

Deregulation of Listeria monocytogenes virulence gene expression by two distinct and semi-independent pathways.

A novel mutation within the central Listeria monocytogenes regulator PrfA that results in constitutive expression of virulence gene products.

Pleiotropic enhancement of bacterial pathogenesis resulting from the constitutive activation of the Listeria monocytogenes regulatory factor PrfA.

How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde.

From hot dogs to host cells: how the bacterial pathogen Listeria monocytogenes regulates virulence gene expression.

Identification of novel Listeria monocytogenes secreted virulence factors following mutational activation of the central virulence regulator, PrfA.

Stimulation of enhanced CD8 T cell responses following immunization with a hyper-antigen secreting intracytosolic bacterial pathogen.

Selected prfA* mutations in recombinant attenuated Listeria monocytogenes strains augment expression of foreign immunogens and enhance vaccine-elicited humoral and cellular immune responses.

Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains.

A novel prfA mutation that promotes Listeria monocytogenes cytosol entry but reduces bacterial spread and cytotoxicity.

Functional impact of mutational activation on the Listeria monocytogenes central virulence regulator PrfA.

The posttranslocation chaperone PrsA2 contributes to multiple facets of Listeria monocytogenes pathogenesis.

Listeria monocytogenes - from saprophyte to intracellular pathogen.

Complete transcriptional profile of an environmental pathogen.

Listeria monocytogenes CtaP is a multifunctional cysteine transport-associated protein required for bacterial pathogenesis.

A bacterial pathogen flips the riboswitch.

The virulence regulator PrfA promotes biofilm formation by Listeria monocytogenes.

Contribution of chitinases to Listeria monocytogenes pathogenesis.

Listeria monocytogenes PrsA2 is required for virulence factor secretion and bacterial viability within the host cell cytosol.

Constitutive activation of PrfA tilts the balance of Listeria monocytogenes fitness towards life within the host versus environmental survival.

Actin polymerization drives septation of Listeria monocytogenes namA hydrolase mutants, demonstrating host correction of a bacterial defect.

Evidence for subpopulations of Listeria monocytogenes with enhanced invasion of cardiac cells.

Functional analysis of the Listeria monocytogenes secretion chaperone PrsA2 and its multiple contributions to bacterial virulence.

A novel C-terminal mutation resulting in constitutive activation of the Listeria monocytogenes central virulence regulatory factor PrfA.

Probing the role of protein surface charge in the activation of PrfA, the central regulator of Listeria monocytogenes pathogenesis.

Listeria monocytogenes adapts to long-term stationary phase survival without compromising bacterial virulence.

Genome sequence of Listeria monocytogenes 07PF0776, a cardiotropic serovar 4b strain.

Optimizing the balance between host and environmental survival skills: lessons learned from Listeria monocytogenes.

Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis.

The Listeria monocytogenes ChiA chitinase enhances virulence through suppression of host innate immunity.

SHIV Antigen Immunization Alters Patterns of Immune Responses to SHIV/Malaria Coinfection and Protects against Life-Threatening SHIV-Related Malaria.

PrfA-like transcription factor gene lmo0753 contributes to L-rhamnose utilization in Listeria monocytogenes strains associated with human food-borne infections.

γδ T cells exhibit multifunctional and protective memory in intestinal tissues.

Roles of a novel Crp/Fnr family transcription factor Lmo0753 in soil survival, biofilm production and surface attachment to fresh produce of Listeria monocytogenes.

Listeria monocytogenes virulence factor secretion: don't leave the cell without a chaperone.

HMBPP-deficient Listeria mutant immunization alters pulmonary/systemic responses, effector functions, and memory polarization of Vγ2Vδ2 T cells.

Identification of a peptide-pheromone that enhances Listeria monocytogenes escape from host cell vacuoles.