Anesthesia Center for Critical Care Research of the Department of Anesthesia,
Critical Care,
and Pain Medicine,
Department of Anesthesia,
Critical Care and Pain Medicine,
Anesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine,
Department of Anesthesia, Critical Care and Pain Medicine
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Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse.
Anesthesiology Apr, 2008 | Pubmed ID: 18362598
In vitro enzyme kinetics of microencapsulated tyrosinase.
Artificial cells, blood substitutes, and immobilization biotechnology Sep-Nov, 2002 | Pubmed ID: 12537404
Effects of long-term oral administration of polymeric microcapsules containing tyrosinase on maintaining decreased systemic tyrosine levels in rats.
Journal of pharmaceutical sciences Apr, 2004 | Pubmed ID: 14999721
Effects of combined oral administration and intravenous injection on maintaining decreased systemic tyrosine levels in rats.
Artificial cells, blood substitutes, and immobilization biotechnology Feb, 2004 | Pubmed ID: 15027806
In vitro and in vivo effects of polyhaemoglobin-tyrosinase on murine B16F10 melanoma.
Melanoma research Jun, 2004 | Pubmed ID: 15179188
Polyhemoglobin-tyrosinase, an oxygen carrier with murine B16F10 melanoma suppression properties: a preliminary report.
Artificial cells, blood substitutes, and immobilization biotechnology May, 2004 | Pubmed ID: 15274434
Polyhemoglobin with different percentage of tetrameric hemoglobin and effects on vasoactivity and electrocardiogram.
Artificial cells, blood substitutes, and immobilization biotechnology , 2006 | Pubmed ID: 16537172
Inhaled nitric oxide enables artificial blood transfusion without hypertension.
Circulation Apr, 2008 | Pubmed ID: 18391111
Prevention of the pulmonary vasoconstrictor effects of HBOC-201 in awake lambs by continuously breathing nitric oxide.
Anesthesiology Jan, 2009 | Pubmed ID: 19104178
Hemoglobin-based red blood cell substitutes and nitric oxide.
Trends in cardiovascular medicine Apr, 2009 | Pubmed ID: 19679268
Endothelial dysfunction enhances vasoconstriction due to scavenging of nitric oxide by a hemoglobin-based oxygen carrier.
Anesthesiology Mar, 2010 | Pubmed ID: 20179495
Hemodynamic responses to a hemoglobin bis-tetramer and its polyethylene glycol conjugate.
Transfusion May, 2012 | Pubmed ID: 22070638
Diabetes augments and inhaled nitric oxide prevents the adverse hemodynamic effects of transfusing syngeneic stored blood in mice.
Transfusion Jul, 2012 | Pubmed ID: 22233290
Pulmonary hypertension in lambs transfused with stored blood is prevented by breathing nitric oxide.
Anesthesiology Mar, 2012 | Pubmed ID: 22293717
Transfusion of stored autologous blood does not alter reactive hyperemia index in healthy volunteers.
Anesthesiology Jul, 2012 | Pubmed ID: 22531338
Inhaled nitric oxide attenuates the adverse effects of transfusing stored syngeneic erythrocytes in mice with endothelial dysfunction after hemorrhagic shock.
Anesthesiology Dec, 2012 | Pubmed ID: 23168426
Hemoglobin infusion does not alter murine pulmonary vascular tone.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society Apr, 2013 | Pubmed ID: 23313572
Soluble guanylate cyclase α1-deficient mice: a novel murine model for primary open angle glaucoma.
PloS one , 2013 | Pubmed ID: 23527308
Deletion of the murine cytochrome P450 Cyp2j locus by fused BAC-mediated recombination identifies a role for Cyp2j in the pulmonary vascular response to hypoxia.
PLoS genetics Nov, 2013 | Pubmed ID: 24278032
Beneficial effects of nitric oxide on outcomes after cardiac arrest and cardiopulmonary resuscitation in hypothermia-treated mice.
Anesthesiology Apr, 2014 | Pubmed ID: 24496125
The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6.
Blood Apr, 2014 | Pubmed ID: 24501215
BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism.
Blood Sep, 2014 | Pubmed ID: 25075125
Autologous transfusion of stored red blood cells increases pulmonary artery pressure.
American journal of respiratory and critical care medicine Oct, 2014 | Pubmed ID: 25162920
Soluble Guanylate Cyclase a1-Deficient Mice: a novel murine model for Primary Open Angle Glaucoma.
Annals of neurosciences Apr, 2013 | Pubmed ID: 25206015
Producing nitric oxide by pulsed electrical discharge in air for portable inhalation therapy.
Science translational medicine Jul, 2015 | Pubmed ID: 26136478
Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension.
Anesthesiology 11, 2016 | Pubmed ID: 27517645
Detection and removal of impurities in nitric oxide generated from air by pulsed electrical discharge.
Nitric oxide : biology and chemistry 11, 2016 | Pubmed ID: 27592386
Electric Plasma-generated Nitric Oxide: Hemodynamic Effects in Patients with Pulmonary Hypertension.
American journal of respiratory and critical care medicine 11, 2016 | Pubmed ID: 27797618
Endothelial dysfunction inhibits the ability of haptoglobin to prevent hemoglobin-induced hypertension.
American journal of physiology. Heart and circulatory physiology Jun, 2017 | Pubmed ID: 28314763
The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase.
Investigative ophthalmology & visual science 09, 2017 | Pubmed ID: 28973329
Pulmonary Delivery of Therapeutic and Diagnostic Gases.
Journal of aerosol medicine and pulmonary drug delivery 04, 2018 | Pubmed ID: 29451844
Development of a portable mini-generator to safely produce nitric oxide for the treatment of infants with pulmonary hypertension.
Nitric oxide : biology and chemistry 05, 2018 | Pubmed ID: 29486304
A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.
Molecular pharmaceutics 05, 2018 | Pubmed ID: 29634905
Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH.
Endocrinology 05, 2018 | Pubmed ID: 29635291
Nitric Oxide Decreases Acute Kidney Injury and Stage 3 Chronic Kidney Disease after Cardiac Surgery.
American journal of respiratory and critical care medicine 11, 2018 | Pubmed ID: 29932345
Inhaled nitric oxide.
British journal of pharmacology 01, 2019 | Pubmed ID: 30288739
Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation.
Transfusion 01, 2019 | Pubmed ID: 30444016
Depletion of Vascular Nitric Oxide Contributes to Poor Outcomes after Cardiac Arrest.
American journal of respiratory and critical care medicine 05, 2019 | Pubmed ID: 30785772
Electrically generated nitric oxide from air: a safe and economical treatment for pulmonary hypertension.
Intensive care medicine 11, 2019 | Pubmed ID: 31451859
Intratracheal injection of nitric oxide, generated from air by pulsed electrical discharge, for the treatment of pulmonary hypertension in awake ambulatory lambs.
Nitric oxide : biology and chemistry 04, 2020 | Pubmed ID: 31982629
Ideation and assessment of a nitric oxide delivery system for spontaneously breathing subjects.
Nitric oxide : biology and chemistry 11, 2020 | Pubmed ID: 32835810
High-Dose Nitric Oxide From Pressurized Cylinders and Nitric Oxide Produced by an Electric Generator From Air.
Respiratory care 02, 2022 | Pubmed ID: 34413210
Caitlin O'Rourke*,1,
Georgia Shelton*,1,2,
Joshua D. Hutcheson3,4,
Megan F. Burke2,
Trejeeve Martyn1,
Timothy E. Thayer2,
Hannah R. Shakartzi1,
Mary D. Buswell1,
Robert E. Tainsh1,
Binglan Yu1,4,
Aranya Bagchi1,4,
David K. Rhee2,4,
Connie Wu1,2,4,
Matthias Derwall5,
Emmanuel S. Buys1,4,
Paul B. Yu3,4,
Kenneth D. Bloch1,2,4,
Elena Aikawa3,4,
Donald B. Bloch1,5,6,
Rajeev Malhotra2,4
1Anesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital,
2Cardiovascular Research Center and Cardiology Division of the Department of Medicine, Massachusetts General Hospital,
3Cardiovascular Division, Brigham and Women's Hospital,
4, Harvard Medical School,
5Department of Anesthesiology, Uniklinik RWTH Aachen, RWTH Aachen University,
6Center for Immunology and Inflammatory Diseases and the Division of Rheumatology, Allergy, and Immunology of the Department of Medicine, Massachusetts General Hospital