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Liya Xu

The Vision Center,
The Saban Research Institute

Children’s Hospital Los Angeles

BIOGRAPHY

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PUBLICATIONS

Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma.

JAMA ophthalmology , | Pubmed ID: 29049475

Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma.

Molecular cancer research : MCR , | Pubmed ID: 30061186

Low 25-Hydroxyvitamin D Concentration Is Not Associated With Refractive Error in Middle-Aged and Older Western Australian Adults.

Translational vision science & technology , | Pubmed ID: 30697464

Aqueous Humor Markers in Retinoblastoma, a Review.

Translational vision science & technology , | Pubmed ID: 31019846

Aqueous Humor Is Superior to Blood as a Liquid Biopsy for Retinoblastoma.

Ophthalmology , | Pubmed ID: 31767439

Variability in retinoblastoma genome stability is driven by age and not heritability.

Genes, chromosomes & cancer , | Pubmed ID: 32390242

Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival.

Molecular cancer research : MCR , | Pubmed ID: 32434859

Simultaneous identification of clinically relevant mutations and copy number alterations in aqueous humor of retinoblastoma eyes.

Ophthalmic genetics , | Pubmed ID: 32799607

Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients.

Translational vision science & technology 09, 2020 | Pubmed ID: 33062393

Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy.

Cancers Mar, 2021 | Pubmed ID: 33805776

Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma.

Cancers Jul, 2021 | Pubmed ID: 34283049

Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy.

NPJ precision oncology Jul, 2021 | Pubmed ID: 34316014

INSTITUTIONS

Children’s Hospital Los Angeles

Keck School of Medicine of the University of Southern California

University of Southern California

JOVE ARTICLES

Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis

Mary E. Kim^1,2,

Liya Xu^1,2,3,11,

Rishvanth K. Prabakar⁴,

Lishuang Shen⁵,

Chen-Ching Peng^1,3,

Peter Kuhn^3,6,7,8,

Xiaowu Gai^5,9,

James Hicks^3,6,10,

Jesse L. Berry^1,2,6,11

¹The Vision Center, Children’s Hospital Los Angeles,

²USC Roski Eye Institute, Keck School of Medicine of the University of Southern California,

³Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California,

⁴Department of Molecular and Computational Biology, University of Southern California,

⁵Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles,

⁶Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California,

⁷Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California,

⁸Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California,

⁹Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC,

¹⁰Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California,

¹¹The Saban Research Institute, Children’s Hospital Los Angeles

Cancer Research

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Liya Xu

The Vision Center,The Saban Research Institute

Children’s Hospital Los Angeles

Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis

The Vision Center,
The Saban Research Institute