Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Jeeshan Singh^1,2, Xiaomei Shan^1,2, Aparna Mahajan^1,2, Martin Herrmann^1,2, Christine Schauer^1,2, Jasmin Knopf^1,2, Luis E. Muñoz^1,2

¹Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, ²Deutsches Zentrum für Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen

Ocular surface inflammation harms the ocular surface tissues and compromises vital functions of the eye. The present protocol describes a method to induce ocular inflammation and collect compromised tissues in a mouse model of Meibomian gland dysfunction (MGD).