Carl W. White

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability.

Redox systems of the cell: possible links and implications.

Elevated expression of hexokinase II protects human lung epithelial-like A549 cells against oxidative injury.

Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor.

Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase.

Composition of coronary atherosclerotic plaques in patients with acute myocardial infarction and stable angina pectoris determined by contrast-enhanced multislice computed tomography.

Thioredoxin liquefies and decreases the viscoelasticity of cystic fibrosis sputum.

Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells.

Potential role for antiangiogenic proteins in the evolution of bronchopulmonary dysplasia.

Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: implications for antioxidant therapy.

Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.

Extracellular ATP-mediated signaling for survival in hyperoxia-induced oxidative stress.

Antioxidant defenses in the preterm lung: role for hypoxia-inducible factors in BPD?

Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells.

Lung epithelial cells release ATP during ozone exposure: signaling for cell survival.

Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung.

Thioredoxin and dihydrolipoic acid inhibit elastase activity in cystic fibrosis sputum.

Effect of preterm birth on hypoxia-inducible factors and vascular endothelial growth factor in primate lungs.

Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling.

Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

Cholesterol interferes with the MTT assay in human epithelial-like (A549) and endothelial (HLMVE and HCAE) cells.

Commentary on "Hypoxia, hypoxic signaling, tissue damage, and detection of reactive oxygen species (ROS)".

Endothelial Akt activation by hyperoxia: role in cell survival.

Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo.

Purinergic signaling and kinase activation for survival in pulmonary oxidative stress and disease.

Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity.

Multislice computed tomography for determination of coronary artery disease in a symptomatic patient population.

Effect of cell cycle growth arrest on global DNA methylation status in human lung epithelial-like (A549) cells.

Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs.

Reduced thioredoxin increases proinflammatory cytokines and neutrophil influx in rat airways: modulation by airway mucus.

HIF stabilizing agents: shotgun or scalpel?

Lipoic acid suppression of neutrophil respiratory burst: effect of NADPH.

Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.

A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death.

Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells.

Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.

Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.

Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

Characterisation of the prostanoid receptor mediating inhibition of smooth muscle contractility in the rat prostate gland.

Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.

Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models.

Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.

The residual nonadrenergic contractile response to nerve stimulation of the mouse prostate is mediated by acetylcholine but not ATP in a comparison with the mouse vas deferens.

Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma.

Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.

Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease.

AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury.

2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.

Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors.

Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.

Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.

Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure.

SERCA2 regulates non-CF and CF airway epithelial cell response to ozone.

Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer.

Suicidal ideation and thought disorder associated with the formoterol component of combined asthma medication.

Tissue Factor Signals Airway Epithelial Basal Cell Survival via Coagulation and PAR1/2.

Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.

Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1α and hypoxia-inducible transcription factor-2α.

Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways.

Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.

Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.

Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.

Impact of SOD-Mimetic Manganoporphyrins on Spin Trapping of Superoxide and Related Artifacts.

Age-related changes in the innervation of the prostate gland: implications for prostate cancer initiation and progression.

Human tracheobronchial basal cells. Normal versus remodeling/repairing phenotypes in vivo and in vitro.

Rho kinase activation mediates adrenergic and cholinergic smooth muscle contractile responses in the mouse prostate gland.

Development of a P2X1-purinoceptor mediated contractile response in the aged mouse prostate gland through slowing down of ATP breakdown.

Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice.

Transcriptome profiling of the newborn mouse lung response to acute ozone exposure.

Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice.

Humidifier and environmental "chILD" risks.

Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.

Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.

Antifibrinolytic Mechanisms in Acute Airway Injury following Sulfur Mustard Analog Inhalation.