Pediatric Airway Research Center,
Department of Pediatrics,
Pediatric Airway Research Center, Department of Pediatrics
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Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.
PloS one , 2012 | Pubmed ID: 23029417
Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability.
Chemical research in toxicology Jul, 2002 | Pubmed ID: 12118999
Redox systems of the cell: possible links and implications.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2002 | Pubmed ID: 12122214
Elevated expression of hexokinase II protects human lung epithelial-like A549 cells against oxidative injury.
American journal of physiology. Lung cellular and molecular physiology Sep, 2002 | Pubmed ID: 12169577
Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12244041
Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase.
American journal of respiratory cell and molecular biology Feb, 2003 | Pubmed ID: 12540485
Composition of coronary atherosclerotic plaques in patients with acute myocardial infarction and stable angina pectoris determined by contrast-enhanced multislice computed tomography.
The American journal of cardiology Mar, 2003 | Pubmed ID: 12633805
Thioredoxin liquefies and decreases the viscoelasticity of cystic fibrosis sputum.
American journal of physiology. Lung cellular and molecular physiology May, 2004 | Pubmed ID: 14695120
Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells.
Antioxidants & redox signaling Feb, 2004 | Pubmed ID: 14713344
Potential role for antiangiogenic proteins in the evolution of bronchopulmonary dysplasia.
Antioxidants & redox signaling Feb, 2004 | Pubmed ID: 14713345
Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: implications for antioxidant therapy.
Antioxidants & redox signaling Feb, 2004 | Pubmed ID: 14713347
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.
Chemico-biological interactions Jan, 2004 | Pubmed ID: 14726155
Extracellular ATP-mediated signaling for survival in hyperoxia-induced oxidative stress.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14761947
Antioxidant defenses in the preterm lung: role for hypoxia-inducible factors in BPD?
Toxicology and applied pharmacology Mar, 2005 | Pubmed ID: 15710178
Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells.
Free radical biology & medicine Apr, 2005 | Pubmed ID: 15780758
Lung epithelial cells release ATP during ozone exposure: signaling for cell survival.
Free radical biology & medicine Jul, 2005 | Pubmed ID: 15964513
Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2005 | Pubmed ID: 16009933
Thioredoxin and dihydrolipoic acid inhibit elastase activity in cystic fibrosis sputum.
American journal of physiology. Lung cellular and molecular physiology Nov, 2005 | Pubmed ID: 16214824
Effect of preterm birth on hypoxia-inducible factors and vascular endothelial growth factor in primate lungs.
Pediatric pulmonology Dec, 2005 | Pubmed ID: 16231377
Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling.
Chest Dec, 2005 | Pubmed ID: 16373860
Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.
Free radical biology & medicine Jan, 2006 | Pubmed ID: 16413417
Cholesterol interferes with the MTT assay in human epithelial-like (A549) and endothelial (HLMVE and HCAE) cells.
International journal of toxicology Jan-Feb, 2006 | Pubmed ID: 16510353
Commentary on "Hypoxia, hypoxic signaling, tissue damage, and detection of reactive oxygen species (ROS)".
Free radical biology & medicine Mar, 2006 | Pubmed ID: 16540387
Endothelial Akt activation by hyperoxia: role in cell survival.
Free radical biology & medicine Apr, 2006 | Pubmed ID: 16545678
Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo.
American journal of physiology. Lung cellular and molecular physiology Oct, 2006 | Pubmed ID: 16679381
Purinergic signaling and kinase activation for survival in pulmonary oxidative stress and disease.
Free radical biology & medicine Jul, 2006 | Pubmed ID: 16781450
Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2006 | Pubmed ID: 16807366
Multislice computed tomography for determination of coronary artery disease in a symptomatic patient population.
The international journal of cardiovascular imaging Jun, 2007 | Pubmed ID: 17160425
Effect of cell cycle growth arrest on global DNA methylation status in human lung epithelial-like (A549) cells.
In vivo (Athens, Greece) Nov-Dec, 2006 | Pubmed ID: 17203780
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs.
American journal of physiology. Lung cellular and molecular physiology Jun, 2007 | Pubmed ID: 17307811
Reduced thioredoxin increases proinflammatory cytokines and neutrophil influx in rat airways: modulation by airway mucus.
Free radical biology & medicine May, 2007 | Pubmed ID: 17395017
HIF stabilizing agents: shotgun or scalpel?
American journal of physiology. Lung cellular and molecular physiology Sep, 2007 | Pubmed ID: 17616644
Lipoic acid suppression of neutrophil respiratory burst: effect of NADPH.
Antioxidants & redox signaling Feb, 2008 | Pubmed ID: 18158760
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.
Mutation research Mar, 2009 | Pubmed ID: 19010443
A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection.
The Journal of pharmacology and experimental therapeutics Mar, 2009 | Pubmed ID: 19064720
Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.
Toxicological sciences : an official journal of the Society of Toxicology Mar, 2009 | Pubmed ID: 19075041
Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death.
American journal of respiratory and critical care medicine May, 2009 | Pubmed ID: 19201925
Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19541651
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.
Free radical biology & medicine Oct, 2009 | Pubmed ID: 19616616
Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.
Free radical biology & medicine Dec, 2009 | Pubmed ID: 19761830
Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.
Free radical biology & medicine May, 2010 | Pubmed ID: 20138141
Characterisation of the prostanoid receptor mediating inhibition of smooth muscle contractility in the rat prostate gland.
Naunyn-Schmiedeberg's archives of pharmacology Apr, 2010 | Pubmed ID: 20180098
Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.
Chemical research in toxicology Jun, 2010 | Pubmed ID: 20469912
Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models.
Proceedings of the American Thoracic Society Jul, 2010 | Pubmed ID: 20601629
Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.
American journal of respiratory and critical care medicine Dec, 2010 | Pubmed ID: 20639443
The residual nonadrenergic contractile response to nerve stimulation of the mouse prostate is mediated by acetylcholine but not ATP in a comparison with the mouse vas deferens.
The Journal of pharmacology and experimental therapeutics Nov, 2010 | Pubmed ID: 20724483
Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma.
Respiratory research , 2010 | Pubmed ID: 20925946
Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.
The Journal of pharmacology and experimental therapeutics Feb, 2011 | Pubmed ID: 20974699
Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease.
Neonatology , 2011 | Pubmed ID: 21071980
AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury.
Free radical biology & medicine Mar, 2011 | Pubmed ID: 21156205
2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.
Toxicology Apr, 2011 | Pubmed ID: 21295104
Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.
American journal of respiratory cell and molecular biology Aug, 2011 | Pubmed ID: 21642592
Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.
Toxicology letters Sep, 2011 | Pubmed ID: 21722719
Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors.
The Journal of pharmacology and experimental therapeutics Dec, 2011 | Pubmed ID: 21885618
Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.
Free radical biology & medicine Dec, 2011 | Pubmed ID: 21920433
Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.
American journal of physiology. Lung cellular and molecular physiology Jan, 2012 | Pubmed ID: 21964405
Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure.
Journal of aerosol medicine and pulmonary drug delivery Feb, 2012 | Pubmed ID: 22007674
SERCA2 regulates non-CF and CF airway epithelial cell response to ozone.
PloS one , 2011 | Pubmed ID: 22096575
Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer.
The Journal of biological chemistry Apr, 2012 | Pubmed ID: 22371491
Suicidal ideation and thought disorder associated with the formoterol component of combined asthma medication.
Pediatric pulmonology Jan, 2013 | Pubmed ID: 22489078
Tissue Factor Signals Airway Epithelial Basal Cell Survival via Coagulation and PAR1/2.
American journal of respiratory cell and molecular biology Oct, 2012 | Pubmed ID: 23065128
Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.
American journal of respiratory cell and molecular biology Apr, 2013 | Pubmed ID: 23258228
Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1α and hypoxia-inducible transcription factor-2α.
American journal of respiratory cell and molecular biology Jul, 2013 | Pubmed ID: 23492195
Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways.
Biochemical and biophysical research communications May, 2013 | Pubmed ID: 23583199
Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.
Toxicology and applied pharmacology Oct, 2013 | Pubmed ID: 23727623
Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.
PloS one , 2013 | Pubmed ID: 23826320
Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.
Toxicology Sep, 2013 | Pubmed ID: 23845566
Impact of SOD-Mimetic Manganoporphyrins on Spin Trapping of Superoxide and Related Artifacts.
Applied magnetic resonance Feb, 2011 | Pubmed ID: 23853422
Age-related changes in the innervation of the prostate gland: implications for prostate cancer initiation and progression.
Organogenesis Jul-Sep, 2013 | Pubmed ID: 23872639
Human tracheobronchial basal cells. Normal versus remodeling/repairing phenotypes in vivo and in vitro.
American journal of respiratory cell and molecular biology Dec, 2013 | Pubmed ID: 23927678
Rho kinase activation mediates adrenergic and cholinergic smooth muscle contractile responses in the mouse prostate gland.
European journal of pharmacology Dec, 2013 | Pubmed ID: 24055190
Development of a P2X1-purinoceptor mediated contractile response in the aged mouse prostate gland through slowing down of ATP breakdown.
Neurourology and urodynamics Nov, 2013 | Pubmed ID: 24249481
Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24297884
Transcriptome profiling of the newborn mouse lung response to acute ozone exposure.
Toxicological sciences : an official journal of the Society of Toxicology Mar, 2014 | Pubmed ID: 24336422
Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie Mar, 2014 | Pubmed ID: 24373750
Humidifier and environmental "chILD" risks.
American journal of respiratory and critical care medicine Jan, 2014 | Pubmed ID: 24381989
Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.
PloS one , 2014 | Pubmed ID: 24416404
Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.
Toxicology Mar, 2014 | Pubmed ID: 24631667
Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.
Pediatric pulmonology Apr, 2014 | Pubmed ID: 24692161
Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.
Mutation research Apr, 2014 | Pubmed ID: 24732344
Antifibrinolytic Mechanisms in Acute Airway Injury following Sulfur Mustard Analog Inhalation.
American journal of respiratory cell and molecular biology May, 2014 | Pubmed ID: 24796565
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