Lorenz Studer

Parthenogenetic stem cells in nonhuman primates.

Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells.

Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression.

Neural transplantation for the treatment of Parkinson's disease.

Making and repairing the mammalian brain--in vitro production of dopaminergic neurons.

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

Nonhuman primate parthenogenetic stem cells.

Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL.

Derivation of midbrain dopamine neurons from human embryonic stem cells.

Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells.

Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain.

Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation.

Derivation of multipotent mesenchymal precursors from human embryonic stem cells.

Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library.

Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft.

Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons.

Embryonic stem cell-derived neurons form functional networks in vitro.

Constitutive gene expression predisposes morphogen-mediated cell fate responses of NT2/D1 and 27X-1 human embryonal carcinoma cells.

Mesenchymal cells.

Derivation of engraftable skeletal myoblasts from human embryonic stem cells.

Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.

Optical bioluminescence imaging of human ES cell progeny in the rodent CNS.

Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.

Therapeutic cloning in individual parkinsonian mice.

High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease.

BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage.

Too much Sonic, too few neurons.

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.

Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain.

Wnt1 overexpression leads to enforced cardiomyogenesis and inhibition of hematopoiesis in murine embryonic stem cells.

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation.

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

Protocols for generating ES cell-derived dopamine neurons.

Induced pluripotent stem cell technology for the study of human disease.

Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent.

Enriched motor neuron populations derived from bacterial artificial chromosome-transgenic human embryonic stem cells.

Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells.

Derivation of neural crest cells from human pluripotent stem cells.

Efficient derivation of functional floor plate tissue from human embryonic stem cells.

Single-molecule analysis reveals changes in the DNA replication program for the POU5F1 locus upon human embryonic stem cell differentiation.

Neuroscience: Excessive mobility interrupted.

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells.

Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling.

IPSCs put to the test.

miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells.

Cell fate plug and play: direct reprogramming and induced pluripotency.

Modelling familial dysautonomia in human induced pluripotent stem cells.

Converting human pluripotent stem cells to neural tissue and neurons to model neurodegeneration.

Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.

Cellular reprogramming: recent advances in modeling neurological diseases.

A poised chromatin platform for TGF-β access to master regulators.

The expanding role of miR-302-367 in pluripotency and reprogramming.

Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells.

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment.

Maturation of spinal motor neurons derived from human embryonic stem cells.

ZFX controls the self-renewal of human embryonic stem cells.

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.

Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression.

Derivation of dopaminergic neurons from pluripotent stem cells.

Adapting human pluripotent stem cells to high-throughput and high-content screening.

Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.

Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs.

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.

Build-a-brain.

Specification of functional cranial placode derivatives from human pluripotent stem cells.

Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells.

Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice.

Human iPSC-based modeling of late-onset disease via progerin-induced aging.

Pluripotent stem cells in regenerative medicine: challenges and recent progress.

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.

Aging in iPS cells.

A cell engineering strategy to enhance the safety of stem cell therapies.

Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model.

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells.

The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.

Moving stem cells to the clinic: potential and limitations for brain repair.

Deciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous System.

Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency.

Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors.

Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation.

Neural Crest Cells from Dual SMAD Inhibition.

When rejuvenation is a problem: challenges of modeling late-onset neurodegenerative disease.

Functional Connectivity under Optogenetic Control Allows Modeling of Human Neuromuscular Disease.

Back and forth in time: Directing age in iPSC-derived lineages.

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.

Pluripotent stem cell-based disease modeling: current hurdles and future promise.

Correction: Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors.

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models.

Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.