Michael Chorny

Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics.

Study of the drug release mechanism from tyrphostin AG-1295-loaded nanospheres by in situ and external sink methods.

Inhibition of aortic allograft vasculopathy by local delivery of platelet-derived growth factor receptor tyrosine-kinase blocker AG-1295.

Development and validation of a stability-indicating high performance liquid chromatographic assay for benoxinate.

Long-term stability study of L-adrenaline injections: Kinetics of sulfonation and racemization pathways of drug degradation.

Locally delivered nanoencapsulated tyrphostin (AGL-2043) reduces neointima formation in balloon-injured rat carotid and stented porcine coronary arteries.

Tyrphostin AGL-2043 eluting stent reduces neointima formation in porcine coronary arteries.

Site-specific delivery of dexamethasone from biodegradable implants reduces formation of pericardial adhesions in rabbits.

Adenoviral gene vector tethering to nanoparticle surfaces results in receptor-independent cell entry and increased transgene expression.

Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles.

High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents.

Single and double emulsion manufacturing techniques of an amphiphilic drug in PLGA nanoparticles: formulations of mithramycin and bioactivity.

A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles.

Predicting in vivo efficacy of potential restenosis therapies by cell culture studies: species-dependent susceptibility of vascular smooth muscle cells.

Site-specific analgesia with sustained release liposomes.

Magnetically responsive biodegradable nanoparticles enhance adenoviral gene transfer in cultured smooth muscle and endothelial cells.

Site-specific gene therapy for cardiovascular disease.

Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields.

Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles.

Magnetic nanoparticles for targeted vascular delivery.

Formulation and in vitro characterization of composite biodegradable magnetic nanoparticles for magnetically guided cell delivery.

Magnetically targeted delivery of therapeutic agents to injured blood vessels for prevention of in-stent restenosis.

Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis.

Site-specific gene delivery to stented arteries using magnetically guided zinc oleate-based nanoparticles loaded with adenoviral vectors.

Adenoviral vector tethering to metal surfaces via hydrolyzable cross-linkers for the modulation of vector release and transduction.

Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis.

Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation.

Real-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media.

Targeting to endothelial cells augments the protective effect of novel dual bioactive antioxidant/anti-inflammatory nanoparticles.