Robert J. Levy

Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus.

Endovascular microcoil gene delivery using immobilized anti-adenovirus antibody for vector tethering.

Thymosin beta4 regulation, expression and function in aortic valve interstitial cells.

Serotonin mechanisms in heart valve disease I: serotonin-induced up-regulation of transforming growth factor-beta1 via G-protein signal transduction in aortic valve interstitial cells.

Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells.

Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis.

Calcification resistance with aluminum-ethanol treated porcine aortic valve bioprostheses in juvenile sheep.

Inhibition of cusp and aortic wall calcification in ethanol- and aluminum-treated bioprosthetic heart valves in sheep: background, mechanisms, and synergism.

The incorporation of an ion channel gene mutation associated with the long QT syndrome (Q9E-hMiRP1) in a plasmid vector for site-specific arrhythmia gene therapy: in vitro and in vivo feasibility studies.

Prevention of polyurethane valve cusp calcification with covalently attached bisphosphonate diethylamino moieties.

Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles.

Delivery and expression of pDNA embedded in collagen matrices.

Ethanol inhibition of porcine bioprosthetic heart valve cusp calcification is enhanced by reduction with sodium borohydride.

Modulation of eomes activity alters the size of the developing heart: implications for in utero cardiac gene therapy.

Transcription factor Egr-1 in calcific aortic valve disease.

Cholesterol-derivatized polyurethane: characterization and endothelial cell adhesion.

Triglycidylamine crosslinking of porcine aortic valve cusps or bovine pericardium results in improved biocompatibility, biomechanics, and calcification resistance: chemical and biological mechanisms.

Prevention of calcification of bioprosthetic heart valve cusp and aortic wall with ethanol and aluminum chloride.

Calcification of tissue heart valve substitutes: progress toward understanding and prevention.

Posttranslational control of a cardiac ion channel transgene in vivo: clarithromycin-hMiRP1-Q9E interactions.

Site specific gene delivery in the cardiovascular system.

Cholesterol-modified polyurethane valve cusps demonstrate blood outgrowth endothelial cell adhesion post-seeding in vitro and in vivo.

Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents.

Serotonin transporter mechanisms and cardiac disease.

Surface heparinization of polyurethane via bromoalkylation of hard segment nitrogens.

Prevention of oxidative degradation of polyurethane by covalent attachment of di-tert-butylphenol residues.

Adenoviral gene vector tethering to nanoparticle surfaces results in receptor-independent cell entry and increased transgene expression.

In-vivo dynamic deformation of the mitral valve anterior leaflet.

Mechanisms of the in vivo inhibition of calcification of bioprosthetic porcine aortic valve cusps and aortic wall with triglycidylamine/mercapto bisphosphonate.

[Animal study of intravascular gene therapy based on polyurethane implantable devices].

Transforming growth factor-beta1 mechanisms in aortic valve calcification: increased alkaline phosphatase and related events.

Biological stability of polyurethane modified with covalent attachment of di-tert-butyl-phenol.

Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles.

In vivo biomechanical assessment of triglycidylamine crosslinked pericardium.

High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents.

Immobilization of plasmid DNA on an anti-DNA antibody modified coronary stent for intravascular site-specific gene therapy.

Local delivery of gene vectors from bare-metal stents by use of a biodegradable synthetic complex inhibits in-stent restenosis in rat carotid arteries.

Site-specific analgesia with sustained release liposomes.

Magnetically responsive biodegradable nanoparticles enhance adenoviral gene transfer in cultured smooth muscle and endothelial cells.

Biomechanical and biologic effects of meniscus stabilization using triglycidyl amine.

SnapShot: calcification of bioprosthetic heart valves.

Fenfluramine disrupts the mitral valve interstitial cell response to serotonin.

Analytical chemistry: The matrix neutralized.

Site-specific gene therapy for cardiovascular disease.

Prevention of polyurethane oxidative degradation with phenolic antioxidants covalently attached to the hard segments: structure-function relationships.

Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields.

Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles.

CD47-dependent molecular mechanisms of blood outgrowth endothelial cell attachment on cholesterol-modified polyurethane.

Micropatterning of three-dimensional electrospun polyurethane vascular grafts.

The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation.

Aortic valve cyclic stretch causes increased remodeling activity and enhanced serotonin receptor responsiveness.

Triglycidyl amine crosslinking combined with ethanol inhibits bioprosthetic heart valve calcification.

Immobilization of gene vectors on bisphosphonate-mediated gene-eluting metal stents using antibody for localized gene delivery.

Formulation and in vitro characterization of composite biodegradable magnetic nanoparticles for magnetically guided cell delivery.

Diminished adhesion and activation of platelets and neutrophils with CD47 functionalized blood contacting surfaces.

Blood flow reprograms lymphatic vessels to blood vessels.

Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis.

Site-specific gene delivery to stented arteries using magnetically guided zinc oleate-based nanoparticles loaded with adenoviral vectors.

Anchoring of self-assembled plasmid DNA/anti-DNA antibody/cationic lipid micelles on bisphosphonate-modified stent for cardiovascular gene delivery.

Adenoviral vector tethering to metal surfaces via hydrolyzable cross-linkers for the modulation of vector release and transduction.

Intracellular signaling mechanisms associated with CD47 modified surfaces.

Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis.

The susceptibility of bioprosthetic heart valve leaflets to oxidation.

Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation.

Real-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media.