Vasanthi Jayaraman

A vibrational spectroscopic investigation of interactions of agonists with GluR0, a prokaryotic glutamate receptor.

Photolysis of gamma-(alpha-carboxy-2-nitrobenzyl)-L-glutamic acid investigated in the mcrosecond time scale by time-resolved FTIR.

IgE binding conformational epitopes of Asp f 3, a major allergen of Aspergillus fumigatus.

Photochemical cleavage and release of carboxylic acids from alpha-keto amides.

Is the isolated ligand binding domain a good model of the domain in the native receptor?

Spectroscopic and kinetic methods for ligand-protein interactions of glutamate receptor.

Chemistry and conformation of the ligand-binding domain of GluR2 subtype of glutamate receptors.

Stereochemistry of glutamate receptor agonist efficacy: engineering a dual-specificity AMPA/kainate receptor.

Conformational changes in the ligand-binding domain of a functional ionotropic glutamate receptor.

Resonance Raman and infrared spectroscopic studies of high-output forms of human soluble guanylyl cyclase.

Evolution of glutamate interactions during binding to a glutamate receptor.

Allosteric mechanism in AMPA receptors: a FRET-based investigation of conformational changes.

Role of the chemical interactions of the agonist in controlling alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor activation.

Water soluble RNA based antagonist of AMPA receptors.

Chemical interplay in the mechanism of partial agonist activation in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

Luminescence resonance energy transfer investigation of conformational changes in the ligand binding domain of a kainate receptor.

Overexpression and functional characterization of the extracellular domain of the human alpha1 glycine receptor.

LRET investigations of conformational changes in the ligand binding domain of a functional AMPA receptor.

Vibrational spectroscopic investigation of the ligand binding domain of kainate receptors.

Subunit arrangement in N-methyl-D-aspartate (NMDA) receptors.

Role of dimer interface in activation and desensitization in AMPA receptors.

Structural landscape of isolated agonist-binding domains from single AMPA receptors.

Conformational changes at the agonist binding domain of the N-methyl-D-aspartic acid receptor.

Structural basis of the Ca2+ inhibitory mechanism of Drosophila Na+/Ca2+ exchanger CALX and its modification by alternative splicing.

Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.

Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism.

Amino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor.

Proton-mediated conformational changes in an acid-sensing ion channel.

RNA based antagonist of NMDA receptors.

Structural dynamics of the glycine-binding domain of the N-methyl-D-aspartate receptor.

Stargazin promotes closure of the AMPA receptor ligand-binding domain.

Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine.

Conformational transitions in the glycine-bound GluN1 NMDA receptor LBD via single-molecule FRET.

A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc.

Dynamic membrane protein topological switching upon changes in phospholipid environment.

Acid-sensing ion channels are tuned to follow high-frequency stimuli.

Conformational Selection and Submillisecond Dynamics of the Ligand-binding Domain of the N-Methyl-d-aspartate Receptor.

Stargazin Modulation of AMPA Receptors.

Dynamic Lipid-dependent Modulation of Protein Topology by Post-translational Phosphorylation.

Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive.