Gwenn A. Garden

Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

Microglia in human immunodeficiency virus-associated neurodegeneration.

p53-dependent cell death signaling in neurons.

Acyclovir responsive brain stem disease after the Ramsay Hunt syndrome.

HIV associated neurodegeneration requires p53 in neurons and microglia.

The multiple roles of p53 in the pathogenesis of HIV associated dementia.

Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI--initial results.

Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport.

Predictors of carotid atherosclerotic plaque progression as measured by noninvasive magnetic resonance imaging.

Potential applications and limitations of proteomics in the study of neurological disease.

Activation of the extrinsic caspase pathway in cultured cortical neurons requires p53-mediated down-regulation of the X-linked inhibitor of apoptosis protein to induce apoptosis.

Microglia biology in health and disease.

The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes.

Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration.

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.

Host and viral factors influencing the pathogenesis of HIV-associated neurocognitive disorders.

Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death.

Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release.

Transcription factor p53 influences microglial activation phenotype.

Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.

Emerging roles of p53 in glial cell function in health and disease.