Heinz Feldmann

Vesicular stomatitis virus vectors expressing avian influenza H5 HA induce cross-neutralizing antibodies and long-term protection.

Rescue of Ebola virus from cDNA using heterologous support proteins.

An animal model for the tickborne flavivirus--Omsk hemorrhagic fever virus.

Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages.

Establishment of conventional and fluorescence resonance energy transfer-based real-time PCR assays for detection of pathogenic New World arenaviruses.

RNA polymerase I-driven minigenome system for Ebola viruses.

Intracellular localization of Crimean-Congo Hemorrhagic Fever (CCHF) virus glycoproteins.

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.

Development of a new vaccine for the prevention of Lassa fever.

Ebola virus VP40 late domains are not essential for viral replication in cell culture.

Effects of Ebola virus glycoproteins on endothelial cell activation and barrier function.

The role of reverse genetics systems in studying viral hemorrhagic fevers.

Therapy and prophylaxis of Ebola virus infections.

Polymorphism of filovirus glycoproteins.

Chimpanzee adenovirus vaccine protects against Zaire Ebola virus.

Ebola and Marburg viruses: pathogenesis and development of countermeasures.

Ebola virus: unravelling pathogenesis to combat a deadly disease.

Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment.

Detection of Ebola virus in oral fluid specimens during outbreaks of Ebola virus hemorrhagic fever in the Republic of Congo.

MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever.

Infection of naive target cells with virus-like particles: implications for the function of ebola virus VP24.

Molecular determinants of Ebola virus virulence in mice.

Generation of an adenoviral vaccine vector based on simian adenovirus 21.

Marburg hemorrhagic fever--the forgotten cousin strikes.

Cross-protection against Marburg virus strains by using a live, attenuated recombinant vaccine.

Structure-function analysis of the soluble glycoprotein, sGP, of Ebola virus.

Tyro3 family-mediated cell entry of Ebola and Marburg viruses.

Assembly and budding of Ebolavirus.

Protective efficacy of neutralizing antibodies against Ebola virus infection.

Rapid molecular strategy for filovirus detection and characterization.

Progress towards the treatment of Ebola haemorrhagic fever.

Rapid and simple detection of Ebola virus by reverse transcription-loop-mediated isothermal amplification.

Proteolytic processing of the Ebola virus glycoprotein is not critical for Ebola virus replication in nonhuman primates.

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus.

Effective post-exposure treatment of Ebola infection.

Production and characterization of monoclonal antibodies against different epitopes of Ebola virus antigens.

Panmicrobial oligonucleotide array for diagnosis of infectious diseases.

Differential expression of the Ebola virus GP(1,2) protein and its fragments in E. coli.

Ebola sGP--the first viral glycoprotein shown to be C-mannosylated.

The ecology of Ebola virus.

Filoviruses: recent advances and future challenges.

Outbreaks of filovirus hemorrhagic fever: time to refocus on the patient.

Development of an immunofiltration-based antigen-detection assay for rapid diagnosis of Ebola virus infection.

Blockage of filoviral glycoprotein processing by use of a protein-based inhibitor.

In vitro and in vivo characterization of recombinant Ebola viruses expressing enhanced green fluorescent protein.

Breakdown of paraendothelial barrier function during Marburg virus infection is associated with early tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1.

Epitopes required for antibody-dependent enhancement of Ebola virus infection.

In vitro evaluation of antisense RNA efficacy against filovirus infection, by use of reverse genetics.

Assessment of a vesicular stomatitis virus-based vaccine by use of the mouse model of Ebola virus hemorrhagic fever.

Mucosal delivery of adenovirus-based vaccine protects against Ebola virus infection in mice.

Cluster of cases of hantavirus pulmonary syndrome in Alberta, Canada.

Generation of biologically contained Ebola viruses.

Person-to-person transmission of Nipah virus in a Bangladeshi community.

Ebola virus matrix protein VP40 uses the COPII transport system for its intracellular transport.

Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates.

Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses.

Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice.

Framework for leadership and training of Biosafety Level 4 laboratory workers.

Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway.

Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge.

Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates.

Disease modeling for Ebola and Marburg viruses.

Replication-deficient ebolavirus as a vaccine candidate.

Single-injection vaccine protects nonhuman primates against infection with marburg virus and three species of ebola virus.

Enhanced protection against Ebola virus mediated by an improved adenovirus-based vaccine.

Adenovirus vectors expressing hantavirus proteins protect hamsters against lethal challenge with andes virus.

Mucosal immunization of cynomolgus macaques with the VSVDeltaG/ZEBOVGP vaccine stimulates strong ebola GP-specific immune responses.

Potential impact of a 2-person security rule on BioSafety Level 4 laboratory workers.

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes.

Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein.

Identification of N-glycans from Ebola virus glycoproteins by matrix-assisted laser desorption/ionisation time-of-flight and negative ion electrospray tandem mass spectrometry.

Potent vesicular stomatitis virus-based avian influenza vaccines provide long-term sterilizing immunity against heterologous challenge.

Preparing a community hospital to manage work-related exposures to infectious agents in BioSafety level 3 and 4 laboratories.

Different potential of C-type lectin-mediated entry between Marburg virus strains.

Truncated hantavirus nucleocapsid proteins for serotyping Sin Nombre, Andes, and Laguna Negra hantavirus infections in humans and rodents.

An antibody directed against the fusion peptide of Junin virus envelope glycoprotein GPC inhibits pH-induced membrane fusion.

Development and evaluation of a simple assay for Marburg virus detection using a reverse transcription-loop-mediated isothermal amplification method.

Factors associated with Marburg hemorrhagic fever: analysis of patient data from Uige, Angola.

Are we any closer to combating Ebola infections?

New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cells.

Postexposure treatment of Marburg virus infection.

Detection of Lassa virus, Mali.

Prospects for immunisation against Marburg and Ebola viruses.

A novel model of lethal Hendra virus infection in African green monkeys and the effectiveness of ribavirin treatment.

Antagonism of type I interferon responses by new world hantaviruses.

Enzyme-linked immunosorbent assay for detection of filovirus species-specific antibodies.

C-type lectins do not act as functional receptors for filovirus entry into cells.

Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entry.

Ebola haemorrhagic fever.

Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques.

Detection of all known filovirus species by reverse transcription-polymerase chain reaction using a primer set specific for the viral nucleoprotein gene.

Progress in filovirus vaccine development: evaluating the potential for clinical use.

Rapid detection of Lassa virus by reverse transcription-loop-mediated isothermal amplification.

Thoracic radiography as a refinement methodology for the study of H1N1 influenza in cynomologus macaques (Macaca fascicularis).

Validation of assays to monitor immune responses in the Syrian golden hamster (Mesocricetus auratus).

Tackling Ebola: new insights into prophylactic and therapeutic intervention strategies.

Truly emerging--a new disease caused by a novel virus.

A new Ebola virus nonstructural glycoprotein expressed through RNA editing.

Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques.

Clinical outcome of henipavirus infection in hamsters is determined by the route and dose of infection.

The use of a mobile laboratory unit in support of patient management and epidemiological surveillance during the 2005 Marburg Outbreak in Angola.

Functional genomics reveals the induction of inflammatory response and metalloproteinase gene expression during lethal Ebola virus infection.

In vitro and in vivo activity of ribavirin against Andes virus infection.

A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus.

Genus-specific recruitment of filovirus ribonucleoprotein complexes into budding particles.

Vesicular stomatitis virus-based vaccine protects hamsters against lethal challenge with Andes virus.

Modern dosimetric tools for (60)Co irradiation at high containment laboratories.

Vesicular stomatitis virus-based Ebola vaccines with improved cross-protective efficacy.

Recombinant vesicular stomatitis virus-based vaccines against Ebola and Marburg virus infections.

Single immunization with a monovalent vesicular stomatitis virus-based vaccine protects nonhuman primates against heterologous challenge with Bundibugyo ebolavirus.

Protective efficacy of a bivalent recombinant vesicular stomatitis virus vaccine in the Syrian hamster model of lethal Ebola virus infection.

Management of accidental exposure to Ebola virus in the biosafety level 4 laboratory, Hamburg, Germany.

Comparative analysis of Ebola virus glycoprotein interactions with human and bat cells.

The Ebola virus glycoprotein and HIV-1 Vpu employ different strategies to counteract the antiviral factor tetherin.

The Ebola virus soluble glycoprotein (sGP) does not affect lymphocyte apoptosis and adhesion to activated endothelium.

Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis.

Assessment of rodents as animal models for Reston ebolavirus.

Antibody-dependent enhancement of Marburg virus infection.

Host response dynamics following lethal infection of rhesus macaques with Zaire ebolavirus.

A neutralizing human monoclonal antibody protects african green monkeys from hendra virus challenge.

Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression.

Clinical aspects of Marburg hemorrhagic fever.

Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry.

Nipah virus transmission in a hamster model.

Pathogenesis and host response in Syrian hamsters following intranasal infection with Andes virus.

Pause on avian flu transmission research.

Vesicular Stomatitis Virus-Based Vaccines for Prophylaxis and Treatment of Filovirus Infections.

Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates.

Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection.

Viral hemorrhagic fevers: advancing the level of treatment.

Animal challenge models of henipavirus infection and pathogenesis.

The variety of study in the field of emerging viruses.

Protective efficacy of neutralizing monoclonal antibodies in a nonhuman primate model of Ebola hemorrhagic fever.

Current ebola vaccines.

Enhanced detection of Rift Valley fever virus using molecular assays on whole blood samples.

The immune response to Nipah virus infection.

The Syrian hamster model of hantavirus pulmonary syndrome.

Recently emerged swine influenza A virus (H2N3) causes severe pneumonia in Cynomolgus macaques.

Development of a minigenome system for Andes virus, a New World hantavirus.

A Hendra virus G glycoprotein subunit vaccine protects African green monkeys from Nipah virus challenge.

The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo.

Inclusion bodies are a site of ebolavirus replication.

Inhibition of Marburg virus budding by nonneutralizing antibodies to the envelope glycoprotein.

A Syrian golden hamster model recapitulating ebola hemorrhagic fever.

Rapid Nipah virus entry into the central nervous system of hamsters via the olfactory route.

Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates.

2009 pandemic H1N1 influenza virus elicits similar clinical course but differential host transcriptional response in mouse, macaque, and swine infection models.

Cathepsin B & L are not required for ebola virus replication.

Novel mutations in Marburg virus glycoprotein associated with viral evasion from antibody mediated immune pressure.

Henipavirus pathogenesis in human respiratory epithelial cells.

A recently isolated Lassa virus from Mali demonstrates atypical clinical disease manifestations and decreased virulence in cynomolgus macaques.

Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates.

Comparison of the pathogenicity of Nipah virus isolates from Bangladesh and Malaysia in the Syrian hamster.

Transmission studies resume for avian flu.

Biosafety Level-4 laboratories in Europe: opportunities for public health, diagnostics, and research.

An upstream open reading frame modulates ebola virus polymerase translation and virus replication.

Experimental Andes virus infection in deer mice: characteristics of infection and clearance in a heterologous rodent host.

Hamster-adapted Sin Nombre virus causes disseminated infection and efficiently replicates in pulmonary endothelial cells without signs of disease.

Animal models for highly pathogenic emerging viruses.

Lethal Crimean-Congo hemorrhagic fever virus infection in interferon α/β receptor knockout mice is associated with high viral loads, proinflammatory responses, and coagulopathy.

Pneumonia from human coronavirus in a macaque model.

Expression profiling of lymph node cells from deer mice infected with Andes virus.

Indirect immunofluorescence assay for the simultaneous detection of antibodies against clinically important old and new world hantaviruses.

Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin.

The adaptive immune response does not influence hantavirus disease or persistence in the Syrian hamster.

Mapping of conserved and species-specific antibody epitopes on the Ebola virus nucleoprotein.

Antibody quality and protection from lethal Ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine.

A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals.

Vaccines for viral hemorrhagic fevers--progress and shortcomings.

Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.

The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters.

Antiviral efficacy of favipiravir against two prominent etiological agents of hantavirus pulmonary syndrome.

Chikungunya virus infection, Brazzaville, Republic of Congo, 2011.

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques.

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques.

Seasonal H3N2 influenza A virus fails to enhance Staphylococcus aureus co-infection in a non-human primate respiratory tract infection model.

Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

Geographic distribution and genetic characterization of Lassa virus in sub-Saharan Mali.

Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus.

Long-term single-dose efficacy of a vesicular stomatitis virus-based Andes virus vaccine in Syrian hamsters.

Ebola virus vaccines: an overview of current approaches.

Foodborne transmission of nipah virus in Syrian hamsters.

Single-dose live-attenuated Nipah virus vaccines confer complete protection by eliciting antibodies directed against surface glycoproteins.

Old World hantaviruses in rodents in New Orleans, Louisiana.

Possible leap ahead in filovirus therapeutics.

Unique strain of Crimean-Congo hemorrhagic fever virus, Mali.

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates.

Pathophysiology of hantavirus pulmonary syndrome in rhesus macaques.

Ebola - A Growing Threat?

African green monkeys recapitulate the clinical experience with replication of live attenuated pandemic influenza virus vaccine candidates.

Differential lymphocyte and antibody responses in deer mice infected with sin nombre hantavirus or Andes hantavirus.

Lymphopenia associated with highly virulent H5N1 virus infection due to plasmacytoid dendritic cell-mediated apoptosis of T cells.

Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes.

Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody.

A Novel Life Cycle Modeling System for Ebola Virus Shows a Genome Length-Dependent Role of VP24 in Virus Infectivity.

Influenza Virus A/Anhui/1/2013 (H7N9) Replicates Efficiently in the Upper and Lower Respiratory Tracts of Cynomolgus Macaques.

Infection with MERS-CoV causes lethal pneumonia in the common marmoset.

Reverse genetics systems as tools for the development of novel therapies against filoviruses.