Robert A. Edwards

Visualization of proteins in acrylamide gels using ultraviolet illumination.

Comparative genomics of closely related salmonellae.

The light-induced reactions of tryptophan with halocompounds.

Trp-999 of beta-galactosidase (Escherichia coli) is a key residue for binding, catalysis, and synthesis of allolactose, the natural lac operon inducer.

Visible fluorescent detection of proteins in polyacrylamide gels without staining.

Robotic radical prostatectomy: a technique to reduce pT2 positive margins.

Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes.

In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.

Impaired TGF-beta responses in peripheral T cells of G alpha i2-/- mice.

Viral metagenomics.

Low-molecular-weight protein tyrosine phosphatases of Bacillus subtilis.

Differential roles for CXCR3 in CD4+ and CD8+ T cell trafficking following viral infection of the CNS.

An application of statistics to comparative metagenomics.

Using pyrosequencing to shed light on deep mine microbial ecology.

Identification of trichloroethanol visualized proteins from two-dimensional polyacrylamide gels by mass spectrometry.

Finding novel genes in bacterial communities isolated from the environment.

The marine viromes of four oceanic regions.

The National Microbial Pathogen Database Resource (NMPDR): a genomics platform based on subsystem annotation.

Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts.

Development of indole chemistry to label tryptophan residues in protein for determination of tryptophan surface accessibility.

Expression of CXC chemokine ligand 10 from the mouse hepatitis virus genome results in protection from viral-induced neurological and liver disease.

Metagenomic and small-subunit rRNA analyses reveal the genetic diversity of bacteria, archaea, fungi, and viruses in soil.

Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease.

Bacterial carbon processing by generalist species in the coastal ocean.

The RAST Server: rapid annotations using subsystems technology.

Phylogenetic classification of short environmental DNA fragments.

Microbial ecology of four coral atolls in the Northern Line Islands.

Biodiversity and biogeography of phages in modern stromatolites and thrombolites.

Comparison of healing after cystotomy and repair with fibrin glue and sutured closure in the porcine model.

Functional metagenomic profiling of nine biomes.

Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha-/- mice.

Viral communities associated with healthy and bleaching corals.

Viral diversity and dynamics in an infant gut.

Taxonomic composition and gene content of a methane-producing microbial community isolated from a biogas reactor.

Bone marrow stem cells for urologic tissue engineering.

Comparative metagenomics reveals host specific metavirulomes and horizontal gene transfer elements in the chicken cecum microbiome.

Comparative study of in vivo lymphatic sealing capability of the porcine thoracic duct using laparoscopic dissection devices.

Metagenomic analysis indicates that stressors induce production of herpes-like viruses in the coral Porites compressa.

The 'buoy' stent: evaluation of a prototype indwelling ureteric stent in a porcine model.

Evaluation of the outcomes of electrosurgical induced bowel injury treated with tissue glue/sealant versus sutured repair in a rabbit model.

Metagenomic analysis of stressed coral holobionts.

Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.

Lysogeny and sporulation in Bacillus isolates from the Gulf of Mexico.

The GAAS metagenomic tool and its estimations of viral and microbial average genome size in four major biomes.

Bovine serum albumin glutaraldehyde for completely sutureless laparoscopic heminephrectomy in a survival porcine model.

NOTCH 信号是形成和自我更新的肿瘤启动所必需的细胞和分泌细胞分化的结肠癌的镇压。

Transposases are the most abundant, most ubiquitous genes in nature.

Accessing the SEED genome databases via Web services API: tools for programmers.

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability.

Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a.

Cytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.

Genome sequence of the human pathogen Vibrio cholerae Amazonia.

Phage-bacteria relationships and CRISPR elements revealed by a metagenomic survey of the rumen microbiome.

PHACTS, a computational approach to classifying the lifestyle of phages.

Characterization of the ELPhiS Prophage from Salmonella enterica serovar Enteritidis strain LK5.

TNF-α Induces Up-Regulation of EGFR Expression and Signaling in Human Colonic Myofibroblasts.

PhiSiGns: an online tool to identify signature genes in phages and design PCR primers for examining phage diversity.

Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut.

Draft genome sequence of the shrimp pathogen Vibrio harveyi CAIM 1792.

Muscle sarcomas and alopecia in A/J mice chronically treated with nicotine.

Genome sequence of the bacterioplanktonic, mixotrophic Vibrio campbellii strain PEL22A, isolated in the Abrolhos Bank.

Genome sequences of the ethanol-tolerant Lactobacillus vini strains LMG 23202T and JP7.8.9.

PhiSpy: a novel algorithm for finding prophages in bacterial genomes that combines similarity- and composition-based strategies.

miR-23a promotes the transition from indolent to invasive colorectal cancer.

Genome-wide study of the defective sucrose fermenter strain of Vibrio cholerae from the Latin American cholera epidemic.

Diversification of the Salmonella fimbriae: a model of macro- and microevolution.

Taxonomic and functional microbial signatures of the endemic marine sponge Arenosclera brasiliensis.

Sequencing of seven haloarchaeal genomes reveals patterns of genomic flux.

Microfluidic PCR combined with pyrosequencing for identification of allelic variants with phenotypic associations among targeted Salmonella genes.

Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH.

Real time metagenomics: using k-mers to annotate metagenomes.

Reference-independent comparative metagenomics using cross-assembly: crAss.

SEED servers: high-performance access to the SEED genomes, annotations, and metabolic models.

Intracellular trafficking of the KV1.3 potassium channel is regulated by the prodomain of a matrix metalloprotease.

Applying Shannon's information theory to bacterial and phage genomes and metagenomes.

A bioinformatic analysis of ribonucleotide reductase genes in phage genomes and metagenomes.

Structure and function of a cyanophage-encoded peptide deformylase.

Multivariate analysis of functional metagenomes.

Explaining microbial phenotypes on a genomic scale: GWAS for microbes.

Circadian clock regulates the host response to Salmonella.

Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron.

Draft Genome Sequence of the Fish Pathogen Piscirickettsia salmonis.

Combining de novo and reference-guided assembly with scaffold_builder.

The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST).

Microbial genomic taxonomy.

The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria.

Angiogenic sprouting is regulated by endothelial cell expression of Slug.

Excited state photoreaction between the indole side chain of tryptophan and halocompounds generates new fluorophores and unique modifications.

Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer.

FOCUS: an alignment-free model to identify organisms in metagenomes using non-negative least squares.

Local genomic adaptation of coral reef-associated microbiomes to gradients of natural variability and anthropogenic stressors.

A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes.

Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions.

Sequencing at sea: challenges and experiences in Ion Torrent PGM sequencing during the 2013 Southern Line Islands Research Expedition.

Microbial taxonomy in the post-genomic era: rebuilding from scratch?

RASTtk: a modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes.

Multidimensional metrics for estimating phage abundance, distribution, gene density, and sequence coverage in metagenomes.

Genomic Comparison of the Closely-Related Salmonella enterica Serovars Enteritidis, Dublin and Gallinarum.