Stephanie L. Gupton

Converging populations of f-actin promote breakage of associated microtubules to spatially regulate microtubule turnover in migrating cells.

A high-speed multispectral spinning-disk confocal microscope system for fluorescent speckle microscopy of living cells.

Simultaneous mapping of filamentous actin flow and turnover in migrating cells by quantitative fluorescent speckle microscopy.

Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin.

Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration.

Filopodia: the fingers that do the walking.

mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration.

Integrin signaling switches the cytoskeletal and exocytic machinery that drives neuritogenesis.

The growth cone cytoskeleton in axon outgrowth and guidance.

Mena binds α5 integrin directly and modulates α5β1 function.

A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching.

Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function.

Seeing Past Cellular Adaptation.

Building Blocks of Functioning Brain: Cytoskeletal Dynamics in Neuronal Development.

Membrane Trafficking in Neuronal Development: Ins and Outs of Neural Connectivity.

TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.

Spatiotemporal organization of exocytosis emerges during neuronal shape change.

Mammalian TRIM67 Functions in Brain Development and Behavior.

Revisiting Netrin-1: One Who Guides (Axons).

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.

Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction.

Mechanistic advances in axon pathfinding.

SNARE-Mediated Exocytosis in Neuronal Development.

The ubiquitylome of developing cortical neurons.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47.