Ying Shen

Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress.

Glutamate release during LTD at cerebellar climbing fiber-Purkinje cell synapses.

BAP, a mammalian BiP-associated protein, is a nucleotide exchange factor that regulates the ATPase activity of BiP.

Manipulation of the oocyte: possible damage to the spindle apparatus.

[Protein phosphatase 2A: its structure, function and activity regulation].

[Prevention of bone loss by estradiol valerate combined with medroxyprogesterone acetate among postmenopausal women with osteopenia].

Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.

Significance of 14-3-3 self-dimerization for phosphorylation-dependent target binding.

Preantral follicle culture as a novel in vitro assay in reproductive toxicology testing in mammalian oocytes.

[Analysis on association of glucocorticoid receptor gene polymorphism with steroid-resistance in idiopathic nephrotic syndrome of children].

[Chronic renal failure in children--report of 65 cases].

Cigarette suppresses the expression of P4Halpha and vascular collagen production.

Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.

[Analysis of the levels of serum total calcium and inorganic phosphate of 2,342 children in Beijing].

ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates.

Crisis induced by an escape from a fat strange set.

Endogenous nitric oxide activation protects against cigarette smoking induced apoptosis in endothelial cells.

The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum.

Phosphorylation of p70s6 kinase is implicated in androgen-induced levator ani muscle anabolism in castrated rats.

Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase.

Non-invasive method to assess genotoxicity of nocodazole interfering with spindle formation in mammalian oocytes.

Genotype-dependent expression of endothelial nitric oxide synthase (eNOS) and its regulatory proteins in cultured endothelial cells.

SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability.

Long-term potentiation of neuronal glutamate transporters.

Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection.

Effect of nuclear actin on endothelial nitric oxide synthase expression.

Regulation of endothelial nitric oxide synthase by small RNA.

Human cytomegalovirus inhibits Akt-mediated eNOS activation through upregulating PTEN (phosphatase and tensin homolog deleted on chromosome 10).

Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells.

Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells.

人类的脯氨酰-4-羟化酶 alpha(I) 转录被介导上游的刺激因素。

Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression.

[A meta-analysis on the effect of cyclophosphamide in treatment of nephrotic syndrome in children].

HCMV infection attenuates hydrogen peroxide induced endothelial apoptosis-- involvement of ERK pathway.

A single nucleotide polymorphism in the matrix metalloproteinase 9 gene (-8202A/G) is associated with thoracic aortic aneurysms and thoracic aortic dissection.

Mechanisms for human cytomegalovirus-induced cytoplasmic p53 sequestration in endothelial cells.

Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection.

Genetic characterization and fine mapping of the blast resistance locus Pigm(t) tightly linked to Pi2 and Pi9 in a broad-spectrum resistant Chinese variety.

Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase.

Genetic variations of the NR3C1 gene in children with sporadic nephrotic syndrome.

Oral administration of Cr(VI) induced oxidative stress, DNA damage and apoptotic cell death in mice.

2-methoxyestradiol induces spindle aberrations, chromosome congression failure, and nondisjunction in mouse oocytes.

Cytosolic phospholipase A(2) alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatment.

TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway.

Intrauterine infection induced oligodendrocyte injury and inducible nitric oxide synthase expression in the developing rat brain.

[Efficacy of neoadjuvant radiochemotherapy in treatment of locally advanced low rectal cancer].

Identification of ERdj3 and OBF-1/BOB-1/OCA-B as direct targets of XBP-1 during plasma cell differentiation.

hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells.

Evidence of a relationship between infant birth weight and later diabetes and impaired glucose regulation in a Chinese population.

Enhanced polarizing microscopy as a new tool in aneuploidy research in oocytes.

BiP mutants that are unable to interact with endoplasmic reticulum DnaJ proteins provide insights into interdomain interactions in BiP.

Biogenesis of short intronic repeat 27-nucleotide small RNA from endothelial nitric-oxide synthase gene.

Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1.

RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice.

Serum amyloid A may potentiate prothrombotic and proinflammatory events in acute coronary syndromes.

Effect of 27nt small RNA on endothelial nitric-oxide synthase expression.

Characteristics of Streptococcus pyogenes strains isolated from Chinese children with scarlet fever.

[A case of inflammatory myofibroblastic tumor in hypopharynx].

[Melamine related urinary calculus and acute renal failure in infants].

[Explanation on "the treatment of the urinary calculus of the infant fed with melamine polluted formula milk"].

[Treatment of adjuvant arthritis in rats with Chinese herbal fumigation: efficacy and mechanism].

Apoptotic-related protein changes induced by hexavalent chromium in mice liver.

Diagnosis and treatment of melamine-associated urinary calculus complicated with acute renal failure in infants and young children.

Ultrasonographic diagnosis of urinary calculus caused by melamine in children.

Blood purification therapy in treatment of acute renal failure in infants with melamine-induced stones.

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells.

Blockade of glutamate transporters facilitates cerebellar synaptic long-term depression.

High macrolide resistance in Streptococcus pyogenes strains isolated from children with pharyngitis in China.

Erythropoietin attenuates white matter damage, proinflammatory cytokine and chemokine induction in developing rat brain after intra-uterine infection.

Thoracic aortic dissection: are matrix metalloproteinases involved?

Cadmium is a novel and independent risk factor for early atherosclerosis mechanisms and in vivo relevance.

Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin.

Efficacy and safety of low dose recombinant tissue-type plasminogen activator for the treatment of acute pulmonary thromboembolism: a randomized, multicenter, controlled trial.

Diagnosis, treatment and follow-up of 25 patients with melamine-induced kidney stones complicated by acute obstructive renal failure in Beijing Children's Hospital.

Antibiotic resistance and molecular analysis of Streptococcus pyogenes isolated from healthy schoolchildren in China.

[Diagnostic significance and management principles of colorectal intraepithelial neoplasia].

[Four new cases with WT1 gene mutations in Chinese patients with Wilms' tumor].

Efficacy and safety of 2-hour urokinase regime in acute pulmonary embolism: a randomized controlled trial.

Low birth weight is associated with components of the metabolic syndrome.

Identification and characterization of the first small molecule inhibitor of MDMX.

Metformin reduces lipid accumulation in macrophages by inhibiting FOXO1-mediated transcription of fatty acid-binding protein 4.

JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter.

Histopathological features of the kidney after acute renal failure from melamine.

Challenges facing venous thromboembolism in China: more public awareness and research needed.

PPARalpha agonist fenofibrate protects the kidney from hypertensive injury in spontaneously hypertensive rats via inhibition of oxidative stress and MAPK activity.

Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway.

Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization.

Ethanol acutely modulates mGluR1-dependent long-term depression in cerebellum.

Therapeutic effects of potassium sodium hydrogen citrate on melamine-induced urinary calculi in China.

Serum lipid profile changes during the menopausal transition in Chinese women: a community-based cohort study.

[Nutritional support to children with chronic kidney disease].

[Introduction to NKF-K/DOQI Clinical Practice Guideline for Nutrition in Children with chronic kidney disease].

[The diagnosis and therapy of pediatric urolithiasis].

[Comparison of bioremediation of polycyclic aromatic hydrocarbons (PAHs) contaminated soil by composting in the spring and winter].

Protein substitution affects glass transition temperature and thermal stability.

Photodynamic therapy for symptomatic circumscribed macular choroidal hemangioma in Chinese patients.

Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma.

Improvement of the CuZn-superoxide dismutase enzyme activity and stability as a therapeutic agent by modification with polysialic acids.

Cerebellar long-term depression is deficient in Niemann-Pick type C disease mice.

[Serum proteomic study of prostate cancer with bone metastasis].

One year follow up of the outcomes of child patients with melamine-related kidney stones in Beijing and surrounding provinces in China.

Expressed cell-penetrating peptides can induce a bystander effect, but passage through the secretory pathway reduces protein transduction activity.

[Evaluate the clinical evidence by evidence-based medicine].

Rheb1 is required for mTORC1 and myelination in postnatal brain development.

Molecular analysis of Streptococcus pyogenes strains isolated from Chinese children with pharyngitis.

Insulin increases glutamate transporter GLT1 in cultured astrocytes.

A novel amphipathic block copolymer coating forming micelle-like aggregates for separation of steroids in open tubular capillary electrochromatography.

[Fundus fluorescein angiography in metastatic choroidal carcinomas and differentiating metastatic choroidal carcinomas from primary choroidal melanomas].

Cloning and expression analysis of six small heat shock protein genes in the common cutworm, Spodoptera litura.

Emerging roles of DNA-PK besides DNA repair.

RNA-driven genetic changes in bacteria and in human cells.

[Investigations of Na+ channels in pancreatic beta cells].

Development of a new open-tubular capillary electrochromatography method for in vitro monitoring of toxic aromatic amines distribution in rat blood.

Detection of RNA-templated double-strand break repair in yeast.

Preparation of poly(N-isopropylacrylamide)-grafted well-controlled 3D skeletal monolith based on E-51 epoxy resin for protein separation.

[Changes of leukotriene D4 in nasal discharge and plasma of patients with persistent allergic rhinitis and the effects of antihistamine].

Non-toxic cadmium concentrations induce vascular inflammation and promote atherosclerosis.

Differential-mode vibrational noise cancellation structure for Metglas/Pb(Zr,Ti)O₃ fiber magnetoelectric laminates.

Magnetoelectric bending-mode structure based on Metglas/Pb(Zr,Ti)O₃ fiber laminates.

Feature-based 3D motif filtering for ribosomal RNA.

The short-term therapeutic effects of TCM for IgA nephropathy in children.

[Glutamate receptors and gamma-aminobutyric acid receptors in pancreatic cells].

[Ethic review of clinical researches in children].

[Incidence, diagnosis and treatment of children's congenital abnormalities of the kidney and urinary tract detected in ultrasound screening].

Mispaired rNMPs in DNA are mutagenic and are targets of mismatch repair and RNases H.

[Pathological changes in rat model of urinary calculus induced by melamine].

Study on the distribution features of bone metastases in prostate cancer.

Sex at the origin: an Asian population of the rice blast fungus Magnaporthe oryzae reproduces sexually.

Differential proteome profiling of pleural effusions from lung cancer and benign inflammatory disease patients.

Screening for significant atherosclerotic renal artery stenosis with a regression model in patients undergoing transradial coronary angiography/intervention.

Authors' response to "Is the routine screening for significant atherosclerotic renal artery stenosis during coronary angiography/intervention indispensable?".

Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion.

Randomized comparison of intracoronary tirofiban versus urokinase as an adjunct to primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: results of the ICTUS-AMI trial.

Glycation of high-density lipoprotein in type 2 diabetes mellitus.

Clinical relevance of angiographic coronary collaterals during primary coronary intervention for acute ST-elevation myocardial infarction.

β2-Adrenoreceptor-Mediated Proliferation Inhibition of Embryonic Pluripotent Stem Cells.

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.

Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling.

Concomitant BET and MAPK blockade for effective treatment of ovarian cancer.

C1q/TNF-related protein 1 links macrophage lipid metabolism to inflammation and atherosclerosis.

Adaptive and Acquired Resistance to EGFR Inhibitors Converge on the MAPK Pathway.

Relationship between intracranial internal carotid artery calcification and enlarged cerebral perivascular space.

C1q/TNF-related protein 1 promotes endothelial barrier dysfunction under disturbed flow.

A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochemistry methods.

Interleukin-6 identified as an important factor in hypoxia- and aldehyde dehydrogenase-based gefitinib adaptive resistance in non-small cell lung cancer cells.

Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer.

Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells.

Data on the expression and role of TREM-1 in the development of in-stent restenosis.

Reduced coronary collateralization in type 2 diabetic patients with chronic total occlusion.

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase.

Donor artery stenosis interactions with diastolic blood pressure on coronary collateral flow in type 2 diabetic patients with chronic total occlusion.

CTRP5 promotes transcytosis and oxidative modification of low-density lipoprotein and the development of atherosclerosis.

Gender does not matter: Add-on repetitive transcranial magnetic stimulation treatment for female methamphetamine dependents.

Relationship of High-Density Lipoprotein-Associated Arylesterase Activity to Systolic Heart Failure in Patients with and without Type 2 Diabetes.

The Role of Monocyte to High-Density Lipoprotein Cholesterol Ratio in Prediction of Carotid Intima-Media Thickness in Patients With Type 2 Diabetes.

Blockade of the forward Na /Ca exchanger suppresses the growth of glioblastoma cells through Ca -mediated cell death.

Lipoprotein (a) interactions with cholesterol-containing lipids on angiographic coronary collateralization in type 2 diabetic patients with chronic total occlusion.

Insulin resistance and dysglycemia are associated with left ventricular remodeling after myocardial infarction in non-diabetic patients.