Andrea Flesken-Nikitin

Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability.

Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice.

Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb+/- mice.

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

Mammary carcinoma suppression by cellular retinoic acid binding protein-II.

Use of multiphoton imaging for studying cell migration in the mouse.

Suppression of melanotroph carcinogenesis leads to accelerated progression of pituitary anterior lobe tumors and medullary thyroid carcinomas in Rb+/- mice.

Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer.

Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts.

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth.

Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.

Toxicity and biomedical imaging of layered nanohybrids in the mouse.

Core-shell silica nanoparticles as fluorescent labels for nanomedicine.

Role of p53 and Rb in ovarian cancer.

Mouse models for cancer stem cell research.

Frequent downregulation of miR-34 family in human ovarian cancers.

Strategies for high-resolution imaging of epithelial ovarian cancer by laparoscopic nonlinear microscopy.

Conditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation.

Mouse prostate cancer cell lines established from primary and postcastration recurrent tumors.

Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.

Wild-type p53 controls cell motility and invasion by dual regulation of MET expression.

MET-dependent cancer invasion may be preprogrammed by early alterations of p53-regulated feedforward loop and triggered by stromal cell-derived HGF.

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.

miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment.

Role of the stem cell niche in the pathogenesis of epithelial ovarian cancers.